EP 1133278 A2 20010919 - DELIVERY OF LIPOSOMAL-ENCAPSULATED ANTIOXIDANTS AND APPLICATIONS THEREOF
Title (en)
DELIVERY OF LIPOSOMAL-ENCAPSULATED ANTIOXIDANTS AND APPLICATIONS THEREOF
Title (de)
VERABREICHUNG LIPOSOMALER ANTIOXIDANTIEN ZUR THERAPEUTISCHEN VERWENDUNG
Title (fr)
ADMINISTRATION D'ANTIOXYDANTS LIPOSOMAUX ENCAPSULES ET LEURS APPLICATIONS
Publication
Application
Priority
- CA 0000806 W 20000707
- US 14254599 P 19990707
Abstract (en)
[origin: WO0103669A2] A liposomal composition comprises a hydrophilic sulfhydryl agent and a lipophilic antioxidant, e.g., N-acetyl cysteine and/or alpha -tocopherol, and a method of delivery by contacting a pulmonary tissue of a mammal with the liposomal composition to achieve a prolonged antioxidant effect.
IPC 1-7
IPC 8 full level
A61K 9/127 (2006.01); A61K 31/198 (2006.01); A61K 31/355 (2006.01); A61K 45/06 (2006.01); A61K 47/24 (2006.01); A61K 47/28 (2006.01); A61P 1/16 (2006.01); A61P 7/00 (2006.01); A61P 7/08 (2006.01); A61P 11/00 (2006.01)
CPC (source: EP)
A61K 9/127 (2013.01); A61K 31/355 (2013.01); A61P 1/16 (2017.12); A61P 7/00 (2017.12); A61P 7/08 (2017.12); A61P 11/00 (2017.12)
Citation (search report)
See references of WO 0103669A2
Citation (examination)
- SUNTRES Z.E. ET AL: "Incorporation of alpha-tocopherol in liposomes promotes the retention of liposome-encapsulated glutathione in rat lung", J. PHARM. PHARMACOL., vol. 46, 1994, pages 23 - 28
- JURIMA-ROMET M. ET AL: "Lung uptake of liposome-entrapped glutathione after intratracheal administration", J. PHARM. PHARMACOL., vol. 43, 1991, pages 6 - 10
- JURIMA-ROMET M. ET AL: "Liposomes and bronchoalveolar lavage fluid: Release of vesicle-entrapped glutathione", INT. J. OF PHARMACEUTICS, vol. 88, 1992, pages 201 - 210
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL
DOCDB simple family (publication)
WO 0103669 A2 20010118; WO 0103669 A3 20010712; AU 6142700 A 20010130; CA 2340757 A1 20010118; EP 1133278 A2 20010919; JP 2003504322 A 20030204
DOCDB simple family (application)
CA 0000806 W 20000707; AU 6142700 A 20000707; CA 2340757 A 20000707; EP 00947706 A 20000707; JP 2001508950 A 20000707