Global Patent Index - EP 1133278 A2

EP 1133278 A2 20010919 - DELIVERY OF LIPOSOMAL-ENCAPSULATED ANTIOXIDANTS AND APPLICATIONS THEREOF

Title (en)

DELIVERY OF LIPOSOMAL-ENCAPSULATED ANTIOXIDANTS AND APPLICATIONS THEREOF

Title (de)

VERABREICHUNG LIPOSOMALER ANTIOXIDANTIEN ZUR THERAPEUTISCHEN VERWENDUNG

Title (fr)

ADMINISTRATION D'ANTIOXYDANTS LIPOSOMAUX ENCAPSULES ET LEURS APPLICATIONS

Publication

EP 1133278 A2 20010919 (EN)

Application

EP 00947706 A 20000707

Priority

  • CA 0000806 W 20000707
  • US 14254599 P 19990707

Abstract (en)

[origin: WO0103669A2] A liposomal composition comprises a hydrophilic sulfhydryl agent and a lipophilic antioxidant, e.g., N-acetyl cysteine and/or alpha -tocopherol, and a method of delivery by contacting a pulmonary tissue of a mammal with the liposomal composition to achieve a prolonged antioxidant effect.

IPC 1-7

A61K 9/127; A61K 31/198; A61K 31/355

IPC 8 full level

A61K 9/127 (2006.01); A61K 31/198 (2006.01); A61K 31/355 (2006.01); A61K 45/06 (2006.01); A61K 47/24 (2006.01); A61K 47/28 (2006.01); A61P 1/16 (2006.01); A61P 7/00 (2006.01); A61P 7/08 (2006.01); A61P 11/00 (2006.01)

CPC (source: EP)

A61K 9/127 (2013.01); A61K 31/355 (2013.01); A61P 1/16 (2017.12); A61P 7/00 (2017.12); A61P 7/08 (2017.12); A61P 11/00 (2017.12)

Citation (search report)

See references of WO 0103669A2

Citation (examination)

  • SUNTRES Z.E. ET AL: "Incorporation of alpha-tocopherol in liposomes promotes the retention of liposome-encapsulated glutathione in rat lung", J. PHARM. PHARMACOL., vol. 46, 1994, pages 23 - 28
  • JURIMA-ROMET M. ET AL: "Lung uptake of liposome-entrapped glutathione after intratracheal administration", J. PHARM. PHARMACOL., vol. 43, 1991, pages 6 - 10
  • JURIMA-ROMET M. ET AL: "Liposomes and bronchoalveolar lavage fluid: Release of vesicle-entrapped glutathione", INT. J. OF PHARMACEUTICS, vol. 88, 1992, pages 201 - 210

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL

DOCDB simple family (publication)

WO 0103669 A2 20010118; WO 0103669 A3 20010712; AU 6142700 A 20010130; CA 2340757 A1 20010118; EP 1133278 A2 20010919; JP 2003504322 A 20030204

DOCDB simple family (application)

CA 0000806 W 20000707; AU 6142700 A 20000707; CA 2340757 A 20000707; EP 00947706 A 20000707; JP 2001508950 A 20000707