Global Patent Index - EP 1133312 B8

EP 1133312 B8 2007-10-17 - SYNERGISTIC USE OF THIAZOLIDINEDIONES WITH GLUCAGON-LIKE PEPTIDE-1 AND AGONISTS THEREOF TO TREAT NON-INSULIN DEPENDENT DIABETES

Title (en)

SYNERGISTIC USE OF THIAZOLIDINEDIONES WITH GLUCAGON-LIKE PEPTIDE-1 AND AGONISTS THEREOF TO TREAT NON-INSULIN DEPENDENT DIABETES

Title (de)

SYNERGITISCHE VERWENDUNG VON THIAZOLIDINEDIONEN UND GLUCAGON-ÄHNLICHEM PEPTID-1 UND DESSEN AGONISTEN FÜR DIE BEHANDLUNG VON NICHT-INSULIN-ABHÄNGIGEN DIABETES

Title (fr)

UTILISATION COMBINEE DE THIAZOLIDINEDIONES ET DE PEPTIDE-1 DE TYPE GLUCAGONE ET D'AGONISTES DE CES DERNIERS POUR TRAITER DIABETES NON INSULINO-DEPENDANT.

Publication

EP 1133312 B8 (EN)

Application

EP 00938173 A

Priority

  • US 0015548 W
  • US 13979499 P

Abstract (en)

[origin: WO0078333A2] Thiazolidinedione (TZD) and its pharmacologically active derivatives can be used, in combination with agonists of glucagon-like peptide-1 (GLP-1), to treat non-insulin dependent diabetes mellitus, optionally with other therapies, by improving glycemic control while minimizing side effects, such as heart hypertrophy and elevated fed-state plasma glucose, which are associated with both TZD and GLP-1 monotherapies. Thus, the co-administration of TZD and GLP-1 helps regulate glucose homeostasis in Type II diabetic patients.

IPC 8 full level (invention and additional information)

A61K 38/22 (2006.01); A61K 31/425 (2006.01); A61K 38/26 (2006.01); A61P 3/08 (2006.01)

CPC (invention and additional information)

A61K 31/425 (2013.01); A61K 38/26 (2013.01)

Combination set (CPC)

  1. A61K 31/425 + A61K 2300/00
  2. A61K 38/26 + A61K 2300/00

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

Designated extension state (EPC)

AL LT LV MK RO SI

EPO simple patent family

WO 0078333 A2 20001228; WO 0078333 A3 20010712; AT 372782 T 20070915; AU 5325200 A 20010109; CA 2349865 A1 20001228; CA 2349865 C 20140819; CY 1106971 T1 20120926; DE 60036367 D1 20071025; DE 60036367 T2 20080529; DK 1133312 T3 20080102; EP 1133312 A2 20010919; EP 1133312 B1 20070912; EP 1133312 B8 20071017; EP 1849475 A1 20071031; ES 2291210 T3 20080301; PT 1133312 E 20071130; SI EP1133312 T1 20080229; US 2004127414 A1 20040701; US 6660716 B1 20031209; US 7223728 B2 20070529; US RE40876 E 20090818

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