EP 1133492 A1 20010919 - PROCESS FOR THE PREPARATION OF PAROXETINE HYDROCHLORIDE
Title (en)
PROCESS FOR THE PREPARATION OF PAROXETINE HYDROCHLORIDE
Title (de)
VERFAHREN ZUR HERSTELLUNG VON PAROXETIN HYDROCHLORID
Title (fr)
PROCEDE DE FABRICATION D'HYDROCHLORURE DE PAROXETINE
Publication
Application
Priority
- GB 9903968 W 19991126
- GB 9826176 A 19981128
Abstract (en)
[origin: WO0032592A1] Crystalline paroxetine hydrochloride propan-2-ol solvate having a modified habit that is more easily desolvated to form the anhydrate is obtained by crystallising from a solution of paroxetine hydrochloride in propan-2-ol to which has been added a habit modifier compound. Form A anhydrate is obtained by heating the crystalline solvate of modified habit in a vacuum oven. Suitable habit modifiers are carboxylic acids and amine salts.
IPC 1-7
IPC 8 full level
A61K 31/4525 (2006.01); A61P 25/16 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01); C07D 405/12 (2006.01)
CPC (source: EP)
A61P 25/16 (2017.12); A61P 25/22 (2017.12); A61P 25/24 (2017.12); C07D 405/12 (2013.01)
Citation (search report)
See references of WO 0032592A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0032592 A1 20000608; AU 1396600 A 20000619; EP 1133492 A1 20010919; GB 9826176 D0 19990120; JP 2002531450 A 20020924
DOCDB simple family (application)
GB 9903968 W 19991126; AU 1396600 A 19991126; EP 99973025 A 19991126; GB 9826176 A 19981128; JP 2000585234 A 19991126