EP 1133506 A2 20010919 - BENZYLMALTOTRIOSIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION
Title (en)
BENZYLMALTOTRIOSIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION
Title (de)
BENZYLMALTOTRIOSIDE ALS INHIBITOREN DER PROLIFERATION VON GLATTEN MUSKELZELLEN
Title (fr)
BENZYLMALTOTRIOSIDES INHIBITEURS DE LA PROLIF RATION DES CELLULES DES MUSCLES LISSES
Publication
Application
Priority
- US 9927775 W 19991123
- US 19880598 A 19981124
Abstract (en)
[origin: WO0031095A2] This invention provides smooth muscle cell proliferation inhibitors of formula (I) having the structure wherein X is (A) wherein R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, R<8>, R<9> and R<10>, are each, independently, hydrogen, acyl of 2-7 carbon atoms, perfluoroacyl of 2-10 carbon atoms, alkyl of 1-6 carbon atoms, perfluoroalkyl of 1-6 carbon atoms, benzoyl, benzyl or -SO3M; M is hydrogen, lithium, sodium, potassium or ammonium; R<11> is hydrogen, alkyl of 1-6 carbon atoms, perfluoroalkyl of 1-6 carbon atomes, halogen, nitrile, nitro, or alkoxy of 1-6 carbon atoms; R<12> is hydrogen, nitro, amino, acylamino of 2-7 carbon atoms, perfluoroacylamino of 2-7 carbon atoms, alkylamino of 1-6 carbon atoms, perfluoroalkylamino of 1-6 carbon atoms, dialklylamino where each alkyl chain is independently 1-6 carbon atoms, perfluorodialklylamino where each alkyl chain is independently 1-6 carbon atoms, alkylsulfonylamino of 1-6 carbon atoms, perfluoroalkyl-sulfonylamino of 1-6 carbon atoms, arylsulfonylamino of 6-10 carbon atoms or arylsulfonylamino substituted with halo of 6-10 carbon atoms; or a pharmaceutically acceptable salt thereof.
IPC 1-7
C07H 3/06; C07H 15/18; A61K 31/70; A61P 9/00; A61P 35/00; A61P 21/00
IPC 8 full level
C07H 15/18 (2006.01); A61K 31/7028 (2006.01); A61P 9/00 (2006.01); A61P 9/04 (2006.01); A61P 9/08 (2006.01); A61P 9/12 (2006.01); A61P 11/06 (2006.01); A61P 21/00 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07H 15/08 (2006.01)
CPC (source: EP)
A61K 31/7028 (2013.01); A61P 9/00 (2017.12); A61P 9/04 (2017.12); A61P 9/08 (2017.12); A61P 9/12 (2017.12); A61P 11/06 (2017.12); A61P 21/00 (2017.12); A61P 29/00 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07H 15/08 (2013.01)
Citation (search report)
See references of WO 0031095A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0031095 A2 20000602; WO 0031095 A3 20010104; AU 1919800 A 20000613; BR 9915643 A 20010807; CA 2350759 A1 20000602; CN 1333778 A 20020130; EP 1133506 A2 20010919; JP 2002530420 A 20020917
DOCDB simple family (application)
US 9927775 W 19991123; AU 1919800 A 19991123; BR 9915643 A 19991123; CA 2350759 A 19991123; CN 99815706 A 19991123; EP 99962844 A 19991123; JP 2000583923 A 19991123