EP 1133552 A2 20010919 - METHODS AND REAGENTS FOR INCREASING PROLIFERATIVE CAPACITY AND PREVENTING REPLICATIVE SENESCENCE
Title (en)
METHODS AND REAGENTS FOR INCREASING PROLIFERATIVE CAPACITY AND PREVENTING REPLICATIVE SENESCENCE
Title (de)
VERFAHREN UND REAGENZIEN ZUR ERHÖHUNG DER VERMEHRUNGFÄHIGKEIT UND ZUR VERHINDERUNG DER REPLIKATIVEN ZELLALTERUNG
Title (fr)
METHODES ET REACTIFS D'AUGMENTATION DE LA CAPACITE PROLIFERATIVE ET DE PREVENTION DE LA SENESCENCE REPLICATIVE
Publication
Application
Priority
- US 9927907 W 19991124
- US 10989198 P 19981125
- US 12054999 P 19990217
Abstract (en)
[origin: WO0031238A2] The present invention relates to methods and reagents for extending the life-span, e.g. the number of mitotic divisions, of a cell. In general, the subject method relies on the activation of a telomerase activity and inhibition of one or both of an Rb/p16 pathway or a p53 pathway.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 8/96 (2006.01); A61K 8/98 (2006.01); A61K 35/12 (2015.01); A61K 38/17 (2006.01); A61K 38/22 (2006.01); A61K 45/00 (2006.01); A61K 45/06 (2006.01); A61K 48/00 (2006.01); A61P 43/00 (2006.01); A61Q 19/08 (2006.01); C12N 9/12 (2006.01)
CPC (source: EP)
A61K 38/1709 (2013.01); A61K 45/06 (2013.01); A61P 17/02 (2017.12); A61P 43/00 (2017.12); C12N 9/1241 (2013.01)
C-Set (source: EP)
Citation (search report)
See references of WO 0031238A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0031238 A2 20000602; WO 0031238 A3 20001109; AU 2156600 A 20000613; CA 2352486 A1 20000602; EP 1133552 A2 20010919; IL 143328 A0 20020421; JP 2002530436 A 20020917
DOCDB simple family (application)
US 9927907 W 19991124; AU 2156600 A 19991124; CA 2352486 A 19991124; EP 99965890 A 19991124; IL 14332899 A 19991124; JP 2000584049 A 19991124