Global Patent Index - EP 1135384 A1

EP 1135384 A1 20010926 - PROCESS FOR THE PRODUCTION OF PAROXETINE HYDROCHLORIDE PROPAN-2-OL SOLVATE

Title (en)

PROCESS FOR THE PRODUCTION OF PAROXETINE HYDROCHLORIDE PROPAN-2-OL SOLVATE

Title (de)

VERFAHREN ZUR HERSTELLUNG VON PAROXETINHYDROCHLORID-PROPAN-2-OLSOLVAT

Title (fr)

PROCEDE DE PRODUCTION D'UN SOLVATE PROPAN-2-OL DE CHLORHYDRATE DE PAROXETINE

Publication

EP 1135384 A1 20010926 (EN)

Application

EP 99973030 A 19991130

Priority

  • GB 9904000 W 19991130
  • GB 9826242 A 19981130

Abstract (en)

[origin: WO0032597A1] Crystalline paroxetine hydrochloride propan-2-ol solvate having a modified habit that is more easily desolvated to form the anhydrate is obtained by crystallising from a solution of paroxetine hydrochloride in propan-2-ol under intense insonation conditions, or in a continuous crystalliser, or which has been seeded with crystals of a paroxetine hydrochloride solvate or anhydrate, especially Form A anhydrate.

IPC 1-7

C07D 405/12; A61K 31/445

IPC 8 full level

A61K 31/4427 (2006.01); A61P 25/16 (2006.01); A61P 25/24 (2006.01); C07D 405/12 (2006.01)

CPC (source: EP)

A61P 25/16 (2017.12); A61P 25/24 (2017.12); C07D 405/12 (2013.01)

Citation (search report)

See references of WO 0032597A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0032597 A1 20000608; AU 1398500 A 20000619; EP 1135384 A1 20010926; GB 9826242 D0 19990120; JP 2002531454 A 20020924

DOCDB simple family (application)

GB 9904000 W 19991130; AU 1398500 A 19991130; EP 99973030 A 19991130; GB 9826242 A 19981130; JP 2000585239 A 19991130