EP 1135687 A1 20010926 - AN IMMUNOASSAY FOR THE DETERMINATION OF TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES IN MAMMALS
Title (en)
AN IMMUNOASSAY FOR THE DETERMINATION OF TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES IN MAMMALS
Title (de)
EIN IMMUNOASSAY ZUM BESTIMMEN VON ÜBERTRAGBAREN SPONGIFORMEN ENCEPHALOPATHIEN IN SÄUGERN
Title (fr)
IMMUNO-ESSAI DE RECHERCHE D'ENCEPHALOPATHIES SPONGIFORMES TRANSMISSIBLES CHEZ LES MAMMIFERES
Publication
Application
Priority
- FI 9900896 W 19991027
- FI 982480 A 19981117
Abstract (en)
[origin: WO0029849A1] The present invention relates to an immunometric method for the determination of prion protein (PrP) in a body tissue or body fluid sample from a non-bovine mammal, said method comprising the steps of subjecting the PrP to a treatment in order to facilitate its extraction and binding to antibodies, and subjecting the PrP from the foregoing step to a) a capture antibody bound or capable of binding to a solid phase, and b) a detecting antibody, and quantifying the signal from the detecting antibody bound to the solid phase. Furthermore, the invention concerns a method for diagnosing a transmissible spongiform encephalopathy (TSE) in a mammal, and a method for screening blood samples, particularly blood samples obtained from human blood donors, to investigate whether a sample is infected by a transmissible spongiform encephalopathy (TSE).
IPC 1-7
IPC 8 full level
G01N 33/53 (2006.01); C07K 16/44 (2006.01); C12P 21/08 (2006.01); G01N 33/534 (2006.01); G01N 33/577 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
G01N 33/6896 (2013.01); G01N 2800/2828 (2013.01)
Citation (search report)
See references of WO 0029849A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0029849 A1 20000525; EP 1135687 A1 20010926; FI 982480 A0 19981117; JP 2002530649 A 20020917
DOCDB simple family (application)
FI 9900896 W 19991027; EP 99954029 A 19991027; FI 982480 A 19981117; JP 2000582801 A 19991027