EP 1137627 A1 20011004 - PROCESS FOR THE PREPARATION OF STROBILURIN INTERMEDIATES
Title (en)
PROCESS FOR THE PREPARATION OF STROBILURIN INTERMEDIATES
Title (de)
VERFAHREN ZUR HERSTELLUNG VON ZWISCHENPRODUKTEN FÜR DIE STROBILURIN SYNTHESE
Title (fr)
PROCEDE DE PREPARATION D'INTERMEDIAIRES DE STROBILURINE
Publication
Application
Priority
- EP 9909705 W 19991209
- GB 9827163 A 19981210
- US 39544599 A 19990914
Abstract (en)
[origin: WO0034229A1] The present invention relates to a novel improved process and intermediates for the process of preparing the oxime intermediates of formula (II) wherein R1 is hydrogen, fluoro or chloro, and R2 is methyl, ethyl, methoxy, ethoxy, trifluoromethyl, trifluoromethoxy, cyano, fluoro, chloro or bromo. The novel process comprises diazotizing an aniline of formula (VI) reacting the resulting diazonium salt with isopropenylacetate of formula (X) and reacting the resulting ketone of formula (XI) with an organic nitrite in the presence of hydrogene chloride, and methylating the resulting ketooxime of formula (VIII) with a methylating agent and reacting the resulting O-methyl ketooxime of formula (IX) with hydroxylamine. The compounds of formula (II) are intermediates for highly active fungicides from the class of the strobilurins.
IPC 1-7
IPC 8 full level
C07B 61/00 (2006.01); C07C 45/00 (2006.01); C07C 49/233 (2006.01); C07C 249/04 (2006.01); C07C 249/08 (2006.01); C07C 249/12 (2006.01); C07C 251/48 (2006.01)
CPC (source: EP)
C07C 45/54 (2013.01); C07C 49/233 (2013.01); C07C 249/08 (2013.01)
Citation (search report)
See references of WO 0034229A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0034229 A1 20000615; AU 1974800 A 20000626; EP 1137627 A1 20011004; JP 2002531540 A 20020924
DOCDB simple family (application)
EP 9909705 W 19991209; AU 1974800 A 19991209; EP 99963458 A 19991209; JP 2000586678 A 19991209