EP 1137636 A1 20011004 - PROCESS FOR PREPARATION OF PAROXETINE MALEATE
Title (en)
PROCESS FOR PREPARATION OF PAROXETINE MALEATE
Title (de)
VERFAHREN ZUR HERSTELLUNG VON PAROXETINMALEAT
Title (fr)
PROCEDE DE PREPARATION DE MALEATE DE PAROXETINE
Publication
Application
Priority
- GB 9904175 W 19991210
- GB 9827387 A 19981211
Abstract (en)
[origin: WO0035873A1] Paroxetine maleate is prepared substantially free of 2-[(3S,4R)-trans-4-(4'-fluorophenyl)-3-(3",4"-methylendioxyphenoxymethyl) piperidin-1-yl]butan-1,4-dioic acid by reaction of paroxetine free base with maleic acid at a temperature range below 40 DEG C, or using an alkanol, or ketone as solvent for the reaction, or an alkanol, hydrocarbon, ketone or ester solvent for recrystallization, or by a combination of suitable temperatures and solvents.
IPC 1-7
IPC 8 full level
A61K 31/4525 (2006.01); A61P 25/16 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); C07D 405/12 (2006.01)
CPC (source: EP)
A61P 25/16 (2017.12); A61P 25/24 (2017.12); A61P 25/28 (2017.12); C07D 405/12 (2013.01)
Citation (search report)
See references of WO 0035873A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0035873 A1 20000622; AU 1987400 A 20000703; EP 1137636 A1 20011004; GB 9827387 D0 19990203; JP 2002532470 A 20021002
DOCDB simple family (application)
GB 9904175 W 19991210; AU 1987400 A 19991210; EP 99963631 A 19991210; GB 9827387 A 19981211; JP 2000588135 A 19991210