EP 1137647 A1 20011004 - THIOUREA INHIBITORS OF HERPES VIRUSES
Title (en)
THIOUREA INHIBITORS OF HERPES VIRUSES
Title (de)
THIOUREA INHIBITOREN VON HERPESVIREN
Title (fr)
THIO-UREES INHIBITRICES DES VIRUS DE L'HERPES
Publication
Application
Priority
- US 9928838 W 19991206
- US 20796198 A 19981209
Abstract (en)
[origin: WO0034268A1] Compounds of formula (I) wherein A is heteroaryl; R9-R12 are independently hydrogen, alkyl of 1 to 4 carbon atoms, perhaloalkyl of 1 to 4 carbon atoms, halogen, alkoxy of 1 to 4 carbon atoms, or cyano, or R9 and R10 or R11 and R12 may be taken together to form aryl of 5 to 7 carbon atoms; W is O, NR6, or is absent; G is aryl or heteroaryl; and X is a bond, -NH, alkyl of 1 to 6 carbon atoms, alkenyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, thioalkyl of 1 to 6 carbon atoms, alkylamino of 1 to 6 carbon atoms, or (CH)J; and J is alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 7 carbon atoms, phenyl or benzyl; and n is an integer from 1 to 6; or a pharmaceutical salt thereof, useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, human herpesviruses-6 and -7, and Kaposi herpesvirus.
IPC 1-7
C07D 405/12; A61K 31/33; A61P 31/12; C07D 213/40; C07D 417/12; C07D 231/56; C07D 233/44; C07D 285/06; C07D 213/75; C07D 307/52; C07D 207/32; C07D 333/20; C07D 277/28; C07D 209/14; C07D 215/12
IPC 8 full level
C07D 295/14 (2006.01); A61K 31/06 (2006.01); A61K 31/075 (2006.01); A61K 31/085 (2006.01); A61K 31/10 (2006.01); A61K 31/11 (2006.01); A61K 31/136 (2006.01); A61K 31/15 (2006.01); A61K 31/165 (2006.01); A61K 31/167 (2006.01); A61K 31/17 (2006.01); A61K 31/175 (2006.01); A61K 31/18 (2006.01); A61K 31/196 (2006.01); A61K 31/215 (2006.01); A61K 31/216 (2006.01); A61K 31/222 (2006.01); A61K 31/27 (2006.01); A61K 31/275 (2006.01); A61K 31/341 (2006.01); A61K 31/40 (2006.01); A61K 31/42 (2006.01); A61K 31/426 (2006.01); A61K 31/433 (2006.01); A61K 31/4439 (2006.01); A61K 31/4453 (2006.01); A61K 31/4458 (2006.01); A61K 31/54 (2006.01); A61K 31/695 (2006.01); A61P 31/12 (2006.01); A61P 31/22 (2006.01); C07C 335/20 (2006.01); C07D 207/12 (2006.01); C07D 207/14 (2006.01); C07D 207/335 (2006.01); C07D 209/14 (2006.01); C07D 211/22 (2006.01); C07D 213/40 (2006.01); C07D 213/75 (2006.01); C07D 215/12 (2006.01); C07D 217/12 (2006.01); C07D 231/12 (2006.01); C07D 231/56 (2006.01); C07D 233/44 (2006.01); C07D 261/08 (2006.01); C07D 277/24 (2006.01); C07D 277/28 (2006.01); C07D 285/06 (2006.01); C07D 307/52 (2006.01); C07D 307/54 (2006.01); C07D 333/20 (2006.01); C07D 405/12 (2006.01); C07D 417/12 (2006.01); C07D 207/32 (2006.01)
CPC (source: EP KR)
A61P 31/12 (2017.12 - EP); A61P 31/22 (2017.12 - EP); C07D 207/335 (2013.01 - EP KR); C07D 209/14 (2013.01 - EP KR); C07D 213/40 (2013.01 - EP KR); C07D 213/75 (2013.01 - EP); C07D 215/12 (2013.01 - EP KR); C07D 217/12 (2013.01 - EP KR); C07D 231/56 (2013.01 - EP KR); C07D 233/44 (2013.01 - EP KR); C07D 277/28 (2013.01 - EP); C07D 285/06 (2013.01 - EP KR); C07D 307/52 (2013.01 - EP KR); C07D 333/20 (2013.01 - EP KR); C07D 405/12 (2013.01 - EP); C07D 417/12 (2013.01 - EP KR)
Citation (search report)
See references of WO 0034268A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0034268 A1 20000615; AU 3111100 A 20000626; BR 9915993 A 20010904; CA 2350996 A1 20000615; CN 1333769 A 20020130; CZ 20012057 A3 20011114; EA 200100635 A1 20011224; EP 1137647 A1 20011004; HU P0104611 A2 20020429; HU P0104611 A3 20021028; IL 143261 A0 20020421; JP 2002531557 A 20020924; KR 20010086090 A 20010907; NO 20012837 D0 20010608; NO 20012837 L 20010719; PL 349043 A1 20020701; ZA 200104318 B 20020826
DOCDB simple family (application)
US 9928838 W 19991206; AU 3111100 A 19991206; BR 9915993 A 19991206; CA 2350996 A 19991206; CN 99815821 A 19991206; CZ 20012057 A 19991206; EA 200100635 A 19991206; EP 99965131 A 19991206; HU P0104611 A 19991206; IL 14326199 A 19991206; JP 2000586715 A 19991206; KR 20017007115 A 20010607; NO 20012837 A 20010608; PL 34904399 A 19991206; ZA 200104318 A 20010525