EP 1140120 A4 20030507 - HUMAN BRAINIAC-5
Title (en)
HUMAN BRAINIAC-5
Title (de)
MENSCHLICHE BRAINIAC-5
Title (fr)
BRAINIAC-5 HUMAINS
Publication
Application
Priority
- US 9930452 W 19991220
- US 11380498 P 19981223
Abstract (en)
[origin: WO0039136A2] The present invention relates to novel Brainiac-5 polypeptides which are members of the Brainiac family. In particular, isolated nucleic acid molecules are provided encoding the human Brainiac-5 polypeptides. Brainiac-5 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of Brainiac-5 activities. Also provided are diagnostic methods for detecting immune and nervous system-related disorders and therapeutic methods for treating, preventing, and/or diagnosing immune and nervous system-related disorders.
IPC 1-7
A61K 35/00; C07H 21/02; C07H 21/04; C12N 1/21; C12N 1/15; C12N 1/19; C12N 5/14; C12N 15/11; C12N 15/63; C12N 15/85; C07K 14/705
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/711 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 1/00 (2006.01); A61P 7/00 (2006.01); A61P 7/06 (2006.01); A61P 19/02 (2006.01); A61P 25/08 (2006.01); A61P 25/16 (2006.01); A61P 25/18 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01); A61P 35/02 (2006.01); A61P 37/00 (2006.01); A61P 37/06 (2006.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12P 21/02 (2006.01)
CPC (source: EP)
A61P 1/00 (2017.12); A61P 7/00 (2017.12); A61P 7/06 (2017.12); A61P 19/02 (2017.12); A61P 25/08 (2017.12); A61P 25/16 (2017.12); A61P 25/18 (2017.12); A61P 25/24 (2017.12); A61P 25/28 (2017.12); A61P 29/00 (2017.12); A61P 35/02 (2017.12); A61P 37/00 (2017.12); A61P 37/06 (2017.12); C07K 14/705 (2013.01)
Citation (search report)
- [XD] DATABASE EMBL [online] 9 January 1996 (1996-01-09), "Drosophila megalogaster putative neurogenic secreted signaling protein (brn) mRNA, complete cds.", XP002228623, retrieved from NCBI Database accession no. U41449
- [XD] DATABASE EMBL [online] 14 January 1998 (1998-01-14), "UDP-galactose-2-acetamido-2-deoxy-D-glucose-3-beta-galactosyltransferase", XP002228624, retrieved from CNBI Database accession no. Y15014
- [XP] DATABASE EMBL [online] 18 January 1999 (1999-01-18), "Human cardiac and pancreatic protein (CAPP)", XP002228625, retrieved from EBI Database accession no. AAW80212 & WO 9844112 A1 19981008 - HUMAN GENOME SCIENCES INC [US], et al
- [XP] DATABASE EMBL [online] 4 August 1999 (1999-08-04), "Homo sapiens chromosome 16 clone CTA-277H1, working draft sequence", XP002228626, retrieved from EBI Database accession no. AC008594
- [XP] DATABASE EMBL [online] 27 September 1999 (1999-09-27), "Human brainiac-3", XP002228627, retrieved from EBI Database accession no. AAY06462 & WO 9931116 A1 19990624 - HUMAN GENOME SCIENCES INC [US], et al
- [XP] DATABASE EMBL [online] 27 September 1999 (1999-09-27), "Human brainiac-3 cDNA", XP002234111, retrieved from EBI Database accession no. AAX87194 & WO 9931116 A1 19990624 - HUMAN GENOME SCIENCES INC [US], et al
- [L] DATABASE EMBL [online] 25 January 2001 (2001-01-25), "Human PRO4397 protein sequence SEQ ID NŸ42;", XP002228628, retrieved from EBI Database accession no. AAB24035 & WO 0053750 A1 20000914 - GENENTECH INC [US], et al
- [L] DATABASE EMBL [online] 25 January 2001 (2001-01-25), "Human PRO4397 nucleotide sequence SEQ ID NŸ41", XP002234112, retrieved from EBI Database accession no. AAC58117 & WO 0053750 A1 20000914 - GENENTECH INC [US], et al
- [A] GOODE S ET AL: "BRAINIAC AND FRINGE ARE SIMILAR PIONEER PROTEINS THAT IMPART SPECIFICITY TO NOTCH SIGNALING DURING DROSOPHILA DEVELOPMENT", COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, NEW YORK, NY, US, vol. 62, 1997, pages 177 - 184, XP001041794
- See references of WO 0039136A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0039136 A2 20000706; WO 0039136 A3 20001102; AU 2202100 A 20000731; CA 2356548 A1 20000706; EP 1140120 A2 20011010; EP 1140120 A4 20030507; JP 2002533109 A 20021008
DOCDB simple family (application)
US 9930452 W 19991220; AU 2202100 A 19991220; CA 2356548 A 19991220; EP 99966502 A 19991220; JP 2000591047 A 19991220