EP 1140360 A1 20011010 - TISSUE COLLECTION DEVICES CONTAINING BIOSENSORS

Title (en)

TISSUE COLLECTION DEVICES CONTAINING BIOSENSORS

Title (de)

BIOSENSOREN ENTHALTENDE GEWEBESAMMELVORRICHTUNGEN

Title (fr)

DISPOSITIFS DE PRELEVEMENT DE TISSU CONTENANT DES BIOCAPTEURS

Publication

EP 1140360 A1 20011010 (EN)

Application

EP 99965340 A 19991227

Priority

US 9931051 W 19991227
US 11417898 P 19981230

Abstract (en)

[origin: WO0038836A1] The present invention provides tissue collection devices, particularly blood collection devices, comprising an electrode. The electrodes may further comprise self-assembled monolayers and capture binding ligands, particularly nucleic acid capture probes. The monolayers may comprise insulators and/or electroconduit-forming species (EFS). The devices may further comprise at least one reagent, including anticoagulants, probe nucleic acids, and lysis reagents. In a further aspect, the invention provides methods of detecting a target analyte in a sample comprising applying an initiation signal to a tissue collection device comprising an electrode. The electrode may comprise a self-assembled monolayer and an assay complex comprising a capture binding ligand, the target analyte and an electron transfer moiety. The methods further comprise detecting electron transfer between the electrode and the electron transfer moiety. The methods may further comprise collecting the sample, for example using blood collection equipment.

IPC 1-7

B01L 3/00; G01N 27/327; C12Q 1/68; G01N 33/48

IPC 8 full level

G01N 33/48 (2006.01); C12M 1/34 (2006.01); C12N 15/09 (2006.01); C12Q 1/00 (2006.01); C12Q 1/68 (2006.01); G01N 1/28 (2006.01); G01N 21/78 (2006.01); G01N 27/02 (2006.01); G01N 27/22 (2006.01); G01N 27/28 (2006.01); G01N 27/416 (2006.01); G01N 27/48 (2006.01); G01N 33/483 (2006.01); G01N 33/53 (2006.01); G01N 33/543 (2006.01); G01N 33/566 (2006.01); G01N 33/58 (2006.01)

CPC (source: EP)

B82Y 15/00 (2013.01); B82Y 30/00 (2013.01); C12Q 1/001 (2013.01); G01N 33/5438 (2013.01); G01N 2610/00 (2013.01)

Citation (search report)

See references of WO 0038836A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0038836 A1 20000706; AU 3128200 A 20000731; CA 2355875 A1 20000706; EP 1140360 A1 20011010; JP 2002533694 A 20021008

DOCDB simple family (application)

US 9931051 W 19991227; AU 3128200 A 19991227; CA 2355875 A 19991227; EP 99965340 A 19991227; JP 2000590780 A 19991227