EP 1140875 A1 20011010 - SULPHONYLOXAZOLAMINES AS THERAPEUTIC ACTIVE INGREDIENTS
Title (en)
SULPHONYLOXAZOLAMINES AS THERAPEUTIC ACTIVE INGREDIENTS
Title (de)
SULFONYLOXAZOLAMINE ALS THERAPEUTISCHE WIRKSTOFFE
Title (fr)
SULFONYLOXAZOLAMINES EN TANT QUE PRINCIPES ACTIFS THERAPEUTIQUES
Publication
Application
Priority
- DE 19858593 A 19981218
- EP 9909335 W 19991201
Abstract (en)
[origin: DE19858593A1] The use of (2-phenyl-4-(phenylsulfonyl)-oxazol-5-yl)-amines (I) as therapeutic agents is new. Sulfonyl-oxazolamines of formula (I) and their salts and solvates are claimed as therapeutic agents. R1, R2 = H, A, (CH2)nAr or 2-6C alkenyl; or NR1R2 = monocyclic saturated heterocycle containing 1 or 2 of N, O and S; Z' = H, A, CF3, NO2, halo, OH, OA, NHA or N(A)2; A = 1-6C alkyl; Ar = phenyl substituted by 1 or 2 Z'; n = 1 or 2. Independent claims are included for: (i) the use of (I) as therapeutic agents; and (ii) pharmaceutical compositions for treating central nervous system (CNS) disorders, containing (I) or their salts or solvates; (iii) preparation of pharmaceutical compositions as in (ii) comprising forming a suitable dosage form from (I) or their salts and solvates together with a solid, liquid or half liquid carrier or auxiliary material and optionally with one or more further active ingredients.
IPC 1-7
C07D 263/48; A61K 31/42; A61P 25/16; A61P 25/18; A61P 25/28; A61P 25/24; A61K 31/421; A61P 25/00
IPC 8 full level
A61K 31/421 (2006.01); A61K 31/454 (2006.01); A61K 31/5377 (2006.01); A61P 25/00 (2006.01); A61P 25/16 (2006.01); A61P 25/18 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); C07D 263/48 (2006.01)
CPC (source: EP US)
A61P 25/00 (2018.01 - EP); A61P 25/16 (2018.01 - EP); A61P 25/18 (2018.01 - EP); A61P 25/24 (2018.01 - EP); A61P 25/28 (2018.01 - EP); C07D 263/48 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
US 6441013 B1 20020827; AR 021896 A1 20020807; AU 1861200 A 20000712; AU 763070 B2 20030710; BR 9916310 A 20011106; CA 2356134 A1 20000629; CN 1146549 C 20040421; CN 1331684 A 20020116; CZ 20012144 A3 20020116; DE 19858593 A1 20000621; EP 1140875 A1 20011010; HK 1043125 A1 20020906; HU P0104834 A2 20020729; HU P0104834 A3 20050628; ID 29966 A 20011025; JP 2002533332 A 20021008; NO 20012965 D0 20010615; NO 20012965 L 20010615; PL 349393 A1 20020715; RU 2232757 C2 20040720; SK 8132001 A3 20020205; WO 0037452 A1 20000629; ZA 200105881 B 20021017
DOCDB simple family (application)
US 86809701 A 20010614; AR P990106528 A 19991217; AU 1861200 A 19991201; BR 9916310 A 19991201; CA 2356134 A 19991201; CN 99814728 A 19991201; CZ 20012144 A 19991201; DE 19858593 A 19981218; EP 9909335 W 19991201; EP 99962190 A 19991201; HK 02104944 A 20020702; HU P0104834 A 19991201; ID 20011555 A 19991201; JP 2000589524 A 19991201; NO 20012965 A 20010615; PL 34939399 A 19991201; RU 2001119273 A 19991201; SK 8132001 A 19991201; ZA 200105881 A 20010717