EP 1141263 A4 20020828 - PRODUCTION OF SOLUBLE RECOMBINANT TRYPSINOGEN ANALOGS
Title (en)
PRODUCTION OF SOLUBLE RECOMBINANT TRYPSINOGEN ANALOGS
Title (de)
HERSTELLUNG VON LÖSLICHEN REKOMBINANTEN TRYPSINANALOGEN
Title (fr)
PRODUCTION D'ANALOGUES DE TRYPSINOGENE DE RECOMBINAISON SOLUBLES
Publication
Application
Priority
- US 9921047 W 19990915
- US 10121398 P 19980921
Abstract (en)
[origin: WO0017332A1] The present invention relates to recombinantly produced trypsin and trypsinogen analogs, including nucleic acids which encode trypsin and trypsinogen analogs. The trypsinogen analogs of the present invention contain modifications of the trypsinogen leader sequence such that the trypsinogen cannot be cleaved by trypsin or trypsin-like enzymes. The present invention also includes processes for producing recombinant trypsinogen analogs which can subsequently be activated.
IPC 1-7
C12N 9/76; C12N 15/11; C12N 15/57; C12N 15/62; C12N 15/79; C12N 15/81
IPC 8 full level
C12N 9/76 (2006.01)
CPC (source: EP)
C12N 9/6427 (2013.01)
Citation (search report)
- [X] EP 0597681 A1 19940518 - LILLY CO ELI [US]
- See references of WO 0017332A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0017332 A1 20000330; AR 021818 A1 20020807; AU 6388499 A 20000410; CA 2343966 A1 20000330; EP 1141263 A1 20011010; EP 1141263 A4 20020828; PE 20001068 A1 20001018
DOCDB simple family (application)
US 9921047 W 19990915; AR P990104729 A 19990920; AU 6388499 A 19990915; CA 2343966 A 19990915; EP 99951445 A 19990915; PE 00095299 A 19990920