EP 1141311 A1 20011010 - PROTECTIVE ANTIGEN OF GROUP A STREPTOCOCCI (SPA)
Title (en)
PROTECTIVE ANTIGEN OF GROUP A STREPTOCOCCI (SPA)
Title (de)
SCHUTZANTIGEN AUS GRUPPE A STREPTOCOCCI (SPA)
Title (fr)
ANTIGENE PROTECTEUR DE STREPTOCOCCI DE GROUPE A (SPA)
Publication
Application
Priority
- US 9930807 W 19991222
- US 11379498 P 19981222
- US 11473098 P 19981231
Abstract (en)
[origin: WO0037648A1] The present invention provides the discovery of a new Streptococcus protective antigen (herein designated Spa) which has been identified and isolated from Streptococci. Spa is a surface antigen distinct from M protein which evokes opsonic antibodies that are protective against multiple serotypes of streptococci. The invention further provides isolated Spa polypeptides, proteins, peptides, and antibodies against the same, as well as nucleic acids encoding Spa polypeptide and peptide antigens. Also provided are methods for identification and isolation of a Spa polypeptide, therapeutic compositions comprised of Spa antigens or antibodies and methods of their use in protecting an animal against a Streptococcus infection.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 35/12 (2015.01); A61K 38/00 (2006.01); A61K 39/09 (2006.01); A61K 39/395 (2006.01); A61P 31/04 (2006.01); C07K 14/315 (2006.01); C07K 16/12 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/31 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP)
A61P 31/04 (2018.01); C07K 14/315 (2013.01); A61K 39/00 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0037648 A1 20000629; AU 2384600 A 20000712; AU 762100 B2 20030619; CA 2353802 A1 20000629; CA 2353802 C 20131001; EP 1141311 A1 20011010; JP 2002533084 A 20021008
DOCDB simple family (application)
US 9930807 W 19991222; AU 2384600 A 19991222; CA 2353802 A 19991222; EP 99967585 A 19991222; JP 2000589702 A 19991222