EP 1147118 A1 20011024 - SUBSTITUTED ALPHA-LINKED DISACCHARIDES
Title (en)
SUBSTITUTED ALPHA-LINKED DISACCHARIDES
Title (de)
SUBSTITUIERTE ALPHA-VERKNÜPFTE DISACCHARIDE
Title (fr)
DISACCHARIDES A LIAISON ALPHA NON SUBSTITUES
Publication
Application
Priority
- US 0000686 W 20000112
- US 11559599 P 19990112
Abstract (en)
[origin: WO0042052A1] A disaccharide compound having formula (I); wherein R2Y2Y1 is bounded to a ring carbon atom adjacent to the alpha glycosidic linkage; W1, W2, W3 and W4 are independently O, NH or S; R8 is hydrogen, hydroxyl or a hydroxyl protecting group; k, m, n, p and r are independently 0 or 1; X1 is a single bond, O, NR9 or S; X2 is O, NR12, S, C(O)O, C(O)S, C(S)O, C(S)S, C(NR12)O or C(O)NR12; Y1 is a single bond, O, NR10 or S; Y2 is O, NR13, S, C(O)O, C(O)S, C(S)O, C(S)S, C(NR13)O or C(O)NR13; Z1 is a single bond, O, NR11 or S; Z2 is O, NR14, S, C(O)O, C(O)S, C(S)O, C(S)S, C(NR14)O or C(O)NR14. A method for preparing the disaccharide compound via an activated anomeric sulfoxide glycosylation reaction. A chemical library comprising the compounds of this invention. A method of treating bacterial infections with the compound.
IPC 1-7
IPC 8 full level
C07H 15/203 (2006.01); C07K 9/00 (2006.01)
CPC (source: EP)
C07H 15/203 (2013.01); C07K 9/008 (2013.01); Y02P 20/55 (2015.11)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0042052 A1 20000720; AU 2848200 A 20000801; EP 1147118 A1 20011024; EP 1147118 A4 20040128
DOCDB simple family (application)
US 0000686 W 20000112; AU 2848200 A 20000112; EP 00906899 A 20000112