EP 1147129 A1 20011024 - SACCHARIDES LINKED TO COMPOUNDS THAT BIND CELL-SURFACE PEPTIDES OR PROTEINS
Title (en)
SACCHARIDES LINKED TO COMPOUNDS THAT BIND CELL-SURFACE PEPTIDES OR PROTEINS
Title (de)
SACCHARIDE GEKOPPELT AN SUBSTANZEN, DIE ZELLOBERFLÄCHENPEPTIDE ODER PROTEINE BINDEN.
Title (fr)
SACCHARIDES PORTES PAR DES COMPOSES SE LIANT A DES PROTEINES OU DES PEPTIDES CELLULAIRES DE SURFACE
Publication
Application
Priority
- US 0000651 W 20000112
- US 11559699 P 19990112
Abstract (en)
[origin: WO0042067A1] A compound which comprises: (i) a saccharide compound having transglycosylase inhibitory activity; and (ii) a second compound that is capable of binding a protein or enzyme involved in cell wall biosynthesis, a precursor used in cell wall biosynthesis, the cell wall surface, or combinations thereof. The saccharide compound is linked directly or through a difunctional linker, to the non-saccharide compound; provided that: when the non-saccharide compound is a hexapeptide or a heptapeptide and the saccharide compound does not contain a phosphate or phosphonate ester, then the saccharide compound is not linked directly to the non-saccharide compound through a glycosidic linkage. The non-saccharide compound includes both "natural" (aglycones that are typically associated with a carbohydrate moiety) and "unnatural" (substances that are not typically associated with carbohydrate moiety) aglycones. Unnatural aglycones can be selected, for example, from peptide-binding dyes.
IPC 1-7
C07K 7/54; C07K 9/00; A61K 38/00; A61K 38/12; A61K 38/14; A61K 38/16; G01N 33/53; G01N 33/543; G01N 33/567; G01N 33/566
IPC 8 full level
C07K 1/04 (2006.01); C07K 9/00 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C07K 1/047 (2013.01); C07K 9/008 (2013.01); A61K 38/00 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0042067 A1 20000720; AU 2606700 A 20000801; EP 1147129 A1 20011024; EP 1147129 A4 20030115
DOCDB simple family (application)
US 0000651 W 20000112; AU 2606700 A 20000112; EP 00904285 A 20000112