EP 1150718 A1 20011107 - CONJUGATES OF LIPIDS AND ANTIMICROBIAL OR ANTINEOPLASTIC DRUGS
Title (en)
CONJUGATES OF LIPIDS AND ANTIMICROBIAL OR ANTINEOPLASTIC DRUGS
Title (de)
KONJUGATE VON LIPIDEN UND ANTIMIKROBIELLEN ODER ANTINEOPLASTISCHEN ARZNEIMITTELN
Title (fr)
CONJUGUES DE LIPIDES ET DE MEDICAMENTS ANTIMICROBIENS OU ANTINEOPLASIQUES
Publication
Application
Priority
- US 9916361 W 19990720
- US 9825847 W 19981204
Abstract (en)
[origin: WO0033883A1] This invention herein describes polar lipid conjugates and methods of achieving delivery to and accumulation of biologically active compounds including drugs into organs, tissues and cells, particularly at physiologically protected sites, at pharmacokinetically useful levels. This polar lipid conjugates of this invention permit drug concentrations to be achieved, especially in such physiologically protected sites, at levels at which such compounds are therapeutically effective after administration of systemic levels much lower than currently attainable otherwise. This technology is appropriate for use with antiproliferative, antineoplastic, antibiotic, antibacterial, antimycotic or antiviral drugs, agents and compounds, for rapid and efficient introduction of such agents, for example across the blood-brain barrier.
IPC 1-7
IPC 8 full level
A61K 47/48 (2006.01)
CPC (source: EP)
A61K 47/543 (2017.07); A61K 47/544 (2017.07)
Citation (search report)
See references of WO 0033884A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0033883 A1 20000615; AU 1628799 A 20000626; AU 5114199 A 20000626; CA 2353832 A1 20000615; EP 1150718 A1 20011107
DOCDB simple family (application)
US 9825847 W 19981204; AU 1628799 A 19981204; AU 5114199 A 19990720; CA 2353832 A 19990720; EP 99935721 A 19990720