EP 1151106 A2 20011107 - METHODS FOR PRODUCING POLYPEPTIDES IN FUNGAL CELLS
Title (en)
METHODS FOR PRODUCING POLYPEPTIDES IN FUNGAL CELLS
Title (de)
VERFAHREN ZUR HERSTELLUNG VON POLYPEPTIDEN IN PILZZELLEN
Title (fr)
TECHNIQUES DE PRODUCTION DE POLYPEPTIDES DANS DES CELLULES FONGIQUES
Publication
Application
Priority
- US 0002864 W 20000202
- US 24195599 A 19990202
Abstract (en)
[origin: WO0046375A2] The present invention relates to methods for producing a polypeptide, comprising: (a) cultivating a mutant of a parent fungal cell under conditions conducive for the production of the polypeptide, wherein the mutant cell comprises a first nucleic acid sequence comprising a modification of one or more genes of a pacC pH signal transduction pathway or homologues thereof, and a second nucleic acid sequence encoding the polypeptide; and (b) isolating the polypeptide from the cultivation medium.
IPC 1-7
C12N 15/31; C12N 15/57; C12N 15/80; C12N 15/01; C12N 9/62; C12N 1/15; C07K 14/38; C12P 21/02; C12R 1/66; C12R 1/19
IPC 8 full level
C07K 14/37 (2006.01); C07K 14/38 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/00 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 9/14 (2006.01); C12N 9/62 (2006.01); C12N 9/88 (2006.01); C12N 9/90 (2006.01); C12N 15/09 (2006.01); C12N 15/31 (2006.01); C12N 15/80 (2006.01); C12P 21/02 (2006.01)
CPC (source: EP)
C07K 14/38 (2013.01); C12N 9/62 (2013.01); C12N 15/80 (2013.01); C12P 21/02 (2013.01)
Citation (search report)
See references of WO 0046375A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0046375 A2 20000810; WO 0046375 A3 20001123; AU 2755300 A 20000825; CN 1268746 C 20060809; CN 1342204 A 20020327; EP 1151106 A2 20011107; JP 2002535990 A 20021029
DOCDB simple family (application)
US 0002864 W 20000202; AU 2755300 A 20000202; CN 00804506 A 20000202; EP 00905971 A 20000202; JP 2000597435 A 20000202