EP 1155013 A1 20011121 - HETEROCYCLIC BENZENESULPHONAMIDE COMPOUNDS AS BRADYKININE ANTAGONISTS
Title (en)
HETEROCYCLIC BENZENESULPHONAMIDE COMPOUNDS AS BRADYKININE ANTAGONISTS
Title (de)
HETEROCYCLISCHE BENZOLSULFONAMIDDERIVATE ALS BRADYKININ ANTAGONISTEN
Title (fr)
COMPOSES HETEROCYCLIQUES DE BENZENESULFONAMIDE EN TANT QU'ANTAGONISTES DE LA BRADYKININE
Publication
Application
Priority
- FR 0000396 W 20000217
- FR 9902412 A 19990226
Abstract (en)
[origin: US6479515B1] The invention concerns compounds selected among the group consisting of (i) compounds of formula (I) wherein: Het1 represents a nitrogenous heterocycle with 5 apices, in particular imidazole, pyrazole, or triazole; Het2 represents a nitrogenous heterocycle with 4, 5 or 6 apices, selected among the heterocycles: (II) wherein R1 and R2 are defined as mentioned in the description; and (ii) their additive salts. The invention also concerns the method for preparing said compounds and their use in therapy, in particular for treating pathologies involving bradykinine.
IPC 1-7
IPC 8 full level
A61P 29/00 (2006.01); C07D 521/00 (2006.01)
CPC (source: EP KR US)
A61P 1/00 (2018.01 - EP); A61P 1/02 (2018.01 - EP); A61P 1/18 (2018.01 - EP); A61P 7/00 (2018.01 - EP); A61P 9/10 (2018.01 - EP); A61P 11/00 (2018.01 - EP); A61P 11/06 (2018.01 - EP); A61P 13/10 (2018.01 - EP); A61P 15/06 (2018.01 - EP); A61P 17/02 (2018.01 - EP); A61P 19/02 (2018.01 - EP); A61P 25/00 (2018.01 - EP); A61P 25/04 (2018.01 - EP); A61P 25/06 (2018.01 - EP); A61P 25/28 (2018.01 - EP); A61P 27/16 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 31/04 (2018.01 - EP); A61P 31/12 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 37/06 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 231/12 (2013.01 - EP KR US); C07D 233/56 (2013.01 - EP KR US); C07D 249/08 (2013.01 - EP KR US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
US 6479515 B1 20021112; AR 022754 A1 20020904; AT E245640 T1 20030815; AU 2809600 A 20000914; BG 105840 A 20020430; BR 0008221 A 20011120; CA 2371853 A1 20000831; CA 2371853 C 20090929; CN 1340050 A 20020313; CZ 20013067 A3 20011114; CZ 303169 B6 20120509; DE 60004017 D1 20030828; DE 60004017 T2 20040701; DK 1155013 T3 20031117; EE 04839 B1 20070615; EE 200100444 A 20021216; EP 1155013 A1 20011121; EP 1155013 B1 20030723; ES 2202059 T3 20040401; FR 2790260 A1 20000901; FR 2790260 B1 20010504; HK 1041267 A1 20020705; HR P20010619 A2 20020831; HU P0200281 A2 20020629; HU P0200281 A3 20030528; ID 29914 A 20011025; IL 144720 A0 20020630; JP 2002537392 A 20021105; JP 4564666 B2 20101020; KR 20010102057 A 20011115; MX PA01008672 A 20030624; NO 20014048 D0 20010820; NO 20014048 L 20010820; NZ 513732 A 20010928; PL 199209 B1 20080829; PL 350234 A1 20021118; PT 1155013 E 20031231; SK 11922001 A3 20011203; SK 286710 B6 20090305; TN SN00031 A1 20051110; WO 0050418 A1 20000831; WO 0050418 A9 20010222; ZA 200106250 B 20020730
DOCDB simple family (application)
US 88996501 A 20010724; AR P000100812 A 20000225; AT 00906414 T 20000217; AU 2809600 A 20000217; BG 10584001 A 20010824; BR 0008221 A 20000217; CA 2371853 A 20000217; CN 00803551 A 20000217; CZ 20013067 A 20000217; DE 60004017 T 20000217; DK 00906414 T 20000217; EE P200100444 A 20000217; EP 00906414 A 20000217; ES 00906414 T 20000217; FR 0000396 W 20000217; FR 9902412 A 19990226; HK 02103040 A 20020423; HR P20010619 A 20010824; HU P0200281 A 20000217; ID 20011795 A 20000217; IL 14472000 A 20000217; JP 2000600999 A 20000217; KR 20017010157 A 20010810; MX PA01008672 A 20000217; NO 20014048 A 20010820; NZ 51373200 A 20000217; PL 35023400 A 20000217; PT 00906414 T 20000217; SK 11922001 A 20000217; TN SN00031 A 20000218; ZA 200106250 A 20010730