Global Patent Index - EP 1155016 A1

EP 1155016 A1 20011121 - PROCESS FOR THE PRODUCTION OF PAROXETINE HYDROCHLORIDE ACETONE SOLVATE

Title (en)

PROCESS FOR THE PRODUCTION OF PAROXETINE HYDROCHLORIDE ACETONE SOLVATE

Title (de)

VERFAHREN ZUR HERSTELLUNG VON PAROXETINHYDROCHLORID-ACETONSOLVAT

Title (fr)

PROCESSUS DE PRODUCTION DE SOLVATE ACETONIQUE D'HYDROCHLORURE DE PAROXETINE

Publication

EP 1155016 A1 20011121 (EN)

Application

EP 99973028 A 19991130

Priority

  • GB 9903996 W 19991130
  • GB 9826178 A 19981130

Abstract (en)

[origin: WO0032595A1] Crystalline paroxetine hydrochloride acetone solvate having a modified habit that is more easily desolvated to form the anhydrate is obtained by crystallising from a solution of paroxetine hydrochloride in acetone to which has been added a habit modifier compound. Form A anhydrate is obtained by heating the crystalline solvate of modified habit in a vacuum oven. Suitable habit modifiers are carboxylic acids and amine salts.

IPC 1-7

C07D 405/12; A61K 31/445

IPC 8 full level

A61K 31/443 (2006.01); A61K 31/451 (2006.01); A61K 31/4525 (2006.01); A61P 25/16 (2006.01); A61P 25/24 (2006.01); C07D 405/12 (2006.01)

CPC (source: EP)

A61K 31/451 (2013.01); A61P 25/16 (2018.01); A61P 25/24 (2018.01); C07D 405/12 (2013.01)

Citation (search report)

See references of WO 0032595A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0032595 A1 20000608; AU 1398100 A 20000619; EP 1155016 A1 20011121; GB 9826178 D0 19990120; JP 2002531453 A 20020924

DOCDB simple family (application)

GB 9903996 W 19991130; AU 1398100 A 19991130; EP 99973028 A 19991130; GB 9826178 A 19981130; JP 2000585237 A 19991130