EP 1155035 A2 20011121 - SYNTHETIC PEPTIDE OF REGULATORY VIRUS PROTEIN R (VPR) OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) AND THE UTILIZATION THEREOF

Title (en)

SYNTHETIC PEPTIDE OF REGULATORY VIRUS PROTEIN R (VPR) OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) AND THE UTILIZATION THEREOF

Title (de)

SYNTHETISCHE PEPTIDE DES REGULATORISCHEN VIRUSPROTEINS R (VPR) DES HUMANEN IMMUNDEFIZIENZVIRUS TYP 1 (HIV-1) UND IHRE VERWENDUNG

Title (fr)

PEPTIDES DE SYNTHESE DE LA PROTEINE VIRALE REGULATRICE (VPR) DU VIRUS DE L'IMMUNODEFICIENCE HUMAINE DE TYPE 1 (VIH1) ET LEUR UTILISATION

Publication

EP 1155035 A2 20011121 (DE)

Application

EP 00918674 A 20000219

Priority

CA 2356390 A 20010817
DE 0000525 W 20000219
DE 19908752 A 19990219
DE 19908766 A 19990219

Abstract (en)

[origin: WO0049038A2] The invention relates to synthetic (s) peptides of regulatory virus protein R (Vpr) of human immunodeficiency virus type 1(HIV-1), especially the total chemical synthesis of 96 aminoacid long Vpr protein (sVpr1-96), a 47 aminoacid long N terminal fragment (sVpr1-47) and a 49 aminoacid long C terminal fragment thereof (sVpr48-96) and to fragments sVpr1-20 and sVpr21-40, in addition to other fragments with approximately 15 aminoacids. Said products are used as HIV-1 regulatory proteins in biological assays and in the analysis of molecular structure and physico-chemical properties of Vpr and its domains or in the production of antibodies directed against Vpr-peptide sequences.

IPC 1-7

C07K 14/16; G01N 33/68; C07K 16/10; A61P 31/18

IPC 8 full level

A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 39/12 (2006.01); A61K 39/395 (2006.01); A61K 47/48 (2006.01); A61K 48/00 (2006.01); A61P 31/18 (2006.01); C07K 1/04 (2006.01); C07K 1/06 (2006.01); C07K 14/16 (2006.01); C07K 16/08 (2006.01); C12N 15/09 (2006.01); C12P 21/08 (2006.01); G01N 30/34 (2006.01); G01N 30/88 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/569 (2006.01)

CPC (source: EP)

A61K 47/6901 (2017.07); A61P 31/18 (2017.12); C07K 14/005 (2013.01); A61K 38/00 (2013.01); C12N 2740/16322 (2013.01)

Citation (search report)

See references of WO 0049038A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0049038 A2 20000824; WO 0049038 A3 20010301; WO 0049038 A9 20010517; CA 2356390 A1 20030217; EP 1155035 A2 20011121; JP 2002540768 A 20021203

DOCDB simple family (application)

DE 0000525 W 20000219; CA 2356390 A 20010817; EP 00918674 A 20000219; JP 2000599775 A 20000219