Global Patent Index - EP 1159431 A2

EP 1159431 A2 20011205 - HUMAN KALLIKREIN-LIKE GENES

Title (en)

HUMAN KALLIKREIN-LIKE GENES

Title (de)

MENSCHLICHE KALLIKREIN GENE

Title (fr)

NOUVEAUX GENES HUMAINS DU TYPE KALLIKREINE

Publication

EP 1159431 A2 20011205 (EN)

Application

EP 00908878 A 20000309

Priority

  • CA 0000258 W 20000309
  • US 12426099 P 19990311
  • US 12738699 P 19990401
  • US 14491999 P 19990721

Abstract (en)

[origin: WO0053747A1] The invention relates to nucleic acid molecules, proteins encoded by such nucleic acid molecules; and use of the proteins and nucleic acid molecules.

IPC 1-7

C12N 15/57; C12N 9/64; C12N 15/63; C07K 16/40; C12Q 1/68; G01N 33/53; A61K 39/395; A61K 48/00; A61K 38/48; A01K 67/027

IPC 8 full level

A01K 67/027 (2006.01); A61K 31/7088 (2006.01); A61K 38/00 (2006.01); A61K 45/00 (2006.01); A61P 35/00 (2006.01); C07K 14/705 (2006.01); C07K 16/40 (2006.01); C12N 9/64 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12N 15/57 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01); A61K 48/00 (2006.01)

CPC (source: EP)

A61P 35/00 (2017.12); C07K 14/705 (2013.01); C12N 9/6445 (2013.01); A01K 2217/05 (2013.01); A01K 2217/075 (2013.01); A61K 48/00 (2013.01); A61K 2039/505 (2013.01); C07K 2319/00 (2013.01)

Citation (search report)

See references of WO 0053776A2

Citation (examination)

  • CRAIG H DAY ET AL.: "Characterization of KLK4 expression and detection of KLK4-specific antibody in prostate cancer patient sera", ONCOGENE, vol. 21, 2002, pages 7114 - 7120
  • ZHIJUN XI ET AL.: "Kallikrein 4 is a predominantly nuclear protein and is overexpressed in prostate cancer", CANCER RESEARCH, vol. 64, 1 April 2004 (2004-04-01), pages 2365 - 2370
  • STEPHEN A MYERS ET AL.: "Kallikrein 4 (KLK4), a new member of the human kallikrein gene family is upregulated by estrogen and progesterone in the juman endometrial cancer line, KLE", THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, vol. 86, no. 5, 2001, pages 2323 - 2326
  • YING DONG ET AL.: "Human kallikrein 4 (KLK4) is highly expressed in serous ovarian carcinomas", CLINICAL CANCER RESEARCH, vol. 7, August 2001 (2001-08-01), pages 2363 - 2371
  • CHRISTINA V. OBIEZU ET AL.: "Higher human kallikrein gene 4 (KLK4) expression indicates poor prognosis on ovarian cancer patients", CLINICAL CANCER RESEARCH, vol. 7, August 2001 (2001-08-01), pages 2380 - 2386
  • ZHIJUN XI ET AL.: "Kallikrein 4 is associated with paclitaxel resistance in ovarian cancer", GYNECOLOGIC ONCOLOGY, vol. 94, 2004, pages 80 - 85
  • MASAZUMI MATSUMURA ET AL.: "Substrates of the prostate-specific Serine protease Prostase/KLK4 defined by positional-scanning peptide libraries", THE PROSTATE, vol. 62, 2005, pages 1 - 13
  • THOMAS K. TAKAYAMA ET AL.: "Characterization of hK4 (Prostase), a Prostate-specific Serine protease: Activation of the precursor of Prostate specific antigen (pro-PSA) and single-chain urokinase-type Plaminogen activator and degradation of prostatic acid phosphatase", BIOCHEMISTRY, vol. 40, 2001, pages 15341 - 15348
  • vol. 39

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0053747 A1 20000914; AU 3139800 A 20000928; AU 3139900 A 20000928; CA 2362885 A1 20000914; CA 2366087 A1 20000914; EP 1159431 A2 20011205; JP 2002538789 A 20021119; WO 0053776 A2 20000914; WO 0053776 A3 20001214

DOCDB simple family (application)

CA 0000259 W 20000309; AU 3139800 A 20000309; AU 3139900 A 20000309; CA 0000258 W 20000309; CA 2362885 A 20000309; CA 2366087 A 20000309; EP 00908878 A 20000309; JP 2000603397 A 20000309