Global Patent Index - EP 1159620 A1

EP 1159620 A1 2001-12-05 - DETECTION OF MTOC DISRUPTING SUBSTANCES

Title (en)

DETECTION OF MTOC DISRUPTING SUBSTANCES

Title (de)

NACHWEIS MTOC VERRENKENDEN SUBSTANZEN

Title (fr)

DETECTION DE SUBSTANCES DE RUPTURE D'INTEGRITE DE CENTRE ORGANISANT LES MICROTUBULES

Publication

EP 1159620 A1 (EN)

Application

EP 00907799 A

Priority

  • GB 0000785 W
  • GB 9905007 A

Abstract (en)

[origin: WO0052478A1] A method is provided for identifying a substance capable of disrupting microtubule organising centre (MTOC) integrity, which method comprises: contacting an Asp polypeptide or homologue thereof, or fragment thereof capable of forming and/or maintaining MTOCs in the absence of the substance, with a candidate substance in the presence of components required for MTOC formation and microtubule nucleation therefrom, and determining whether the substance disrupts MTOC integrity.

IPC 1-7 (main, further and additional classification)

G01N 33/68; A61K 45/00; C07K 7/00

IPC 8 full level (invention and additional information)

C07K 14/435 (2006.01); C07K 16/18 (2006.01)

CPC (invention and additional information)

C07K 14/43581 (2013.01); C07K 16/18 (2013.01)

Citation (search report)

See references of WO 0052478A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0052478 A1 20000908; AT 295543 T 20050515; AU 2927100 A 20000921; DE 60020087 D1 20050616; DE 60020087 T2 20060119; EP 1159620 A1 20011205; EP 1159620 B1 20050511; EP 1159620 B8 20050706; GB 9905007 D0 19990428

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