Global Patent Index - EP 1161142 A1

EP 1161142 A1 2001-12-12 - METHODS FOR CULTURING FLUID-FILLED SENSORY ORGANS

Title (en)

METHODS FOR CULTURING FLUID-FILLED SENSORY ORGANS

Title (de)

KULTURVERFAHREN FÜR FLÜSSIGKEITSGEFÜLLTE SENSORISCHE ORGANE

Title (fr)

PROCEDE DE CULTURE D'ORGANES SENSORIELS REMPLIS DE FLUIDES

Publication

EP 1161142 A1 (EN)

Application

EP 00914825 A

Priority

  • US 0005736 W
  • US 12310099 P

Abstract (en)

[origin: WO0054583A1] The present invention provides methods for culturing fluid-filled sensory organs in vitro. In particular, the present invention provides methods for culturing the eyeball, including the retina, and the inner ear, including the Organ of Corti, in vitro. The methods of the present invention involve little or no microsurgical dissection of the entire fluid-filled sensory organ, thereby preserving the structural and functional integrity of the sensory epithelium. The methods of the present invention include the steps of (a) introducing a fluid-filled sensory organ (such as an inner ear or an eye ball) into a culture chamber containing liquid culture medium and (b) moving the culture chamber so that the fluid-filled sensory organ moves within the culture chamber. Preferably the culture chamber is cylindrical or annular in shape and is rotated about its longitudinal axis.

IPC 1-7 (main, further and additional classification)

A01N 1/02; C12M 3/00; C12M 3/02

IPC 8 full level (invention and additional information)

A61K 38/17 (2006.01); C12N 5/0793 (2010.01); A61K 48/00 (2006.01)

CPC (invention and additional information)

C12N 5/062 (2013.01); A61K 38/1709 (2013.01); A61K 48/00 (2013.01); C12N 2501/40 (2013.01); C12N 2501/60 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0054583 A1 20000921; AU 3616400 A 20001004; CA 2364024 A1 20000921; EP 1161142 A1 20011212; EP 1161142 A4 20030122

INPADOC legal status


2004-04-07 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20031001

2003-01-22 [A4] DESPATCH OF SUPPLEMENTARY SEARCH REPORT

- Effective date: 20021209

2003-01-22 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2003-01-15 [RIC1] CLASSIFICATION (CORRECTION)

- Free text: 7C 12N 5/08 A, 7A 01N 1/02 B, 7C 12M 3/02 B, 7C 12M 3/00 B, 7C 12N 5/06 B

2002-06-05 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: OTOGENE USA, INC.

2002-06-05 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: OTOGENE AKTIENGESELLSCHAFT

2002-01-02 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: OTOGENE USA, INC.

2002-01-02 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: KIL, JONATHAN

2002-01-02 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: LOWENHEIM, HUBERT

2002-01-02 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: SUDRA, ANISH H.

2001-12-12 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20010926

2001-12-12 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-12-12 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI