EP 1161142 A1 20011212 - METHODS FOR CULTURING FLUID-FILLED SENSORY ORGANS
Title (en)
METHODS FOR CULTURING FLUID-FILLED SENSORY ORGANS
Title (de)
KULTURVERFAHREN FÜR FLÜSSIGKEITSGEFÜLLTE SENSORISCHE ORGANE
Title (fr)
PROCEDE DE CULTURE D'ORGANES SENSORIELS REMPLIS DE FLUIDES
Publication
Application
Priority
- US 0005736 W 20000303
- US 12310099 P 19990305
Abstract (en)
[origin: WO0054583A1] The present invention provides methods for culturing fluid-filled sensory organs in vitro. In particular, the present invention provides methods for culturing the eyeball, including the retina, and the inner ear, including the Organ of Corti, in vitro. The methods of the present invention involve little or no microsurgical dissection of the entire fluid-filled sensory organ, thereby preserving the structural and functional integrity of the sensory epithelium. The methods of the present invention include the steps of (a) introducing a fluid-filled sensory organ (such as an inner ear or an eye ball) into a culture chamber containing liquid culture medium and (b) moving the culture chamber so that the fluid-filled sensory organ moves within the culture chamber. Preferably the culture chamber is cylindrical or annular in shape and is rotated about its longitudinal axis.
IPC 1-7
IPC 8 full level
A61K 38/17 (2006.01); C12N 5/06 (2006.01); C12N 5/0793 (2010.01); A61K 48/00 (2006.01)
CPC (source: EP)
A61K 38/1709 (2013.01); C12N 5/062 (2013.01); A61K 48/00 (2013.01); C12N 2501/40 (2013.01); C12N 2501/60 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0054583 A1 20000921; AU 3616400 A 20001004; CA 2364024 A1 20000921; EP 1161142 A1 20011212; EP 1161142 A4 20030122
DOCDB simple family (application)
US 0005736 W 20000303; AU 3616400 A 20000303; CA 2364024 A 20000303; EP 00914825 A 20000303