EP 1161231 A2 20011212 - METHOD OF INHIBITING A CHAPERONE PROTEIN
Title (en)
METHOD OF INHIBITING A CHAPERONE PROTEIN
Title (de)
VERFAHREN ZUR HEMMUNG EINES CHAPERONPROTEINS
Title (fr)
METHODE UTILISEE POUR INHIBER UNE PROTEINE CHAPERONNE
Publication
Application
Priority
- US 0006482 W 20000310
- US 12413599 P 19990312
Abstract (en)
[origin: WO0053169A2] The present invention provides a method of inhibiting binding of a chaperone protein with its client protein or client polypeptide. This method comprises contacting coumarin or a coumarin derivative with a chaperone protein, such that the coumarin or the coumarin derivative binds the chaperone protein, which inhibits the chaperon protein from binding its client protein or client polypeptide.
IPC 1-7
IPC 8 full level
C12N 9/99 (2006.01); A61K 31/353 (2006.01); A61K 31/37 (2006.01); A61K 31/7048 (2006.01); A61K 31/7052 (2006.01); A61P 31/20 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 311/10 (2006.01); C07D 311/46 (2006.01); C07D 311/56 (2006.01); C07H 17/075 (2006.01)
CPC (source: EP)
A61K 31/37 (2013.01); A61K 31/7048 (2013.01); A61P 31/20 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12)
Citation (search report)
See references of WO 0053169A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0053169 A2 20000914; WO 0053169 A8 20010111; AU 3740600 A 20000928; AU 776652 B2 20040916; CA 2367108 A1 20000914; EP 1161231 A2 20011212; JP 2003523313 A 20030805
DOCDB simple family (application)
US 0006482 W 20000310; AU 3740600 A 20000310; CA 2367108 A 20000310; EP 00916277 A 20000310; JP 2000603658 A 20000310