Global Patent Index - EP 1161231 A2

EP 1161231 A2 2001-12-12 - METHOD OF INHIBITING A CHAPERONE PROTEIN

Title (en)

METHOD OF INHIBITING A CHAPERONE PROTEIN

Title (de)

VERFAHREN ZUR HEMMUNG EINES CHAPERONPROTEINS

Title (fr)

METHODE UTILISEE POUR INHIBER UNE PROTEINE CHAPERONNE

Publication

EP 1161231 A2 (EN)

Application

EP 00916277 A

Priority

  • US 0006482 W
  • US 12413599 P

Abstract (en)

[origin: WO0053169A2] The present invention provides a method of inhibiting binding of a chaperone protein with its client protein or client polypeptide. This method comprises contacting coumarin or a coumarin derivative with a chaperone protein, such that the coumarin or the coumarin derivative binds the chaperone protein, which inhibits the chaperon protein from binding its client protein or client polypeptide.

IPC 1-7 (main, further and additional classification)

A61K 31/00

IPC 8 full level (invention and additional information)

C12N 9/99 (2006.01); A61K 31/353 (2006.01); A61K 31/37 (2006.01); A61K 31/7048 (2006.01); A61K 31/7052 (2006.01); A61P 31/20 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 311/10 (2006.01); C07D 311/46 (2006.01); C07D 311/56 (2006.01); C07H 17/075 (2006.01)

CPC (invention and additional information)

A61K 31/7048 (2013.01); A61K 31/37 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0053169 A2 20000914; WO 0053169 A8 20010111; AU 3740600 A 20000928; AU 776652 B2 20040916; CA 2367108 A1 20000914; EP 1161231 A2 20011212; JP 2003523313 A 20030805

INPADOC legal status


2008-08-13 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20080115

2007-10-10 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20070911

2001-12-12 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20011011

2001-12-12 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-12-12 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL;LT;LV;MK;RO;SI