Global Patent Index - EP 1161236 A1

EP 1161236 A1 20011212 - DIHYDROXY OPEN-ACID AND SALTS OF HMG-CO-A REDUCTASE INHIBITORS

Title (en)

DIHYDROXY OPEN-ACID AND SALTS OF HMG-CO-A REDUCTASE INHIBITORS

Title (de)

DIHYDROXY OFFEN-SÄURE UND SALZE VON HMG-CO-A REDUCTASE INHIBITOREN

Title (fr)

ACIDE OUVERT EN DIHYDROXY ET SELS D'INHIBITEURS DE LA HMG-CO-A REDUCTASE

Publication

EP 1161236 A1 20011212 (EN)

Application

EP 00907111 A 20000202

Priority

  • US 0002626 W 20000202
  • US 12322799 P 19990308
  • US 26474499 A 19990309

Abstract (en)

[origin: WO0053173A1] The instant invention provides methods and pharmaceutical compositions for inhibiting HMG-CoA reductase, as well as for treating and/or reducing the risk for diseases and conditions affected by inhibition of HMG-CoA reductase, comprising orally administering a therapeutically effective amount of a compound selected from a dihydroxy open acid statin and a pharmaceutically acceptable salt or ester thereof in a delayed-release pharmaceutical dosage form to a patient in need of such treatment wherein substantial release of the compound from the dosage form is delayed until after passage of the dosage form through the stomach.

IPC 1-7

A61K 31/22; A61P 3/06; A61K 9/28

IPC 8 full level

A61K 9/16 (2006.01); A61K 9/28 (2006.01); A61K 9/52 (2006.01); A61K 31/194 (2006.01); A61K 31/40 (2006.01); A61K 31/4418 (2006.01); A61K 31/47 (2006.01); A61K 31/505 (2006.01); A61K 47/10 (2006.01); A61K 47/14 (2006.01); A61K 47/30 (2006.01); A61P 3/06 (2006.01); A61P 9/10 (2006.01); A61P 43/00 (2006.01)

CPC (source: EP)

A61K 9/2833 (2013.01); A61P 3/06 (2017.12); A61P 9/00 (2017.12); A61P 9/10 (2017.12); A61P 43/00 (2017.12)

Citation (search report)

See references of WO 0053173A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0053173 A1 20000914; AR 022856 A1 20020904; AU 2866400 A 20000928; CA 2364253 A1 20000914; CO 5150193 A1 20020429; EP 1161236 A1 20011212; JP 2000256191 A 20000919; JP 2002538202 A 20021112; PE 20001559 A1 20010116; SV 2002000036 A 20020205

DOCDB simple family (application)

US 0002626 W 20000202; AR P000101006 A 20000307; AU 2866400 A 20000202; CA 2364253 A 20000202; CO 00016008 A 20000306; EP 00907111 A 20000202; JP 2000062746 A 20000307; JP 2000603662 A 20000202; PE 0002012000 A 20000307; SV 2000000036 A 20000308