Global Patent Index - EP 1161540 A1

EP 1161540 A1 2001-12-12 - GENETIC MANIPULATION OF ISOFLAVONOIDS

Title (en)

GENETIC MANIPULATION OF ISOFLAVONOIDS

Title (de)

GENETISCHE VERÄNDERUNG VON ISOFLAVONOIDEN

Title (fr)

MANIPULATION GENETIQUE D'ISOFLAVONOIDES

Publication

EP 1161540 A1 (EN)

Application

EP 00916134 A

Priority

  • US 0005915 W
  • US 12326799 P

Abstract (en)

[origin: WO0053771A1] Soybean and Medicago truncatula CYP93C genes have been isolated which encode a cytochrome P450 that can catalyze the aryl migration of a flavanone to yield an isoflavanone intermediate or an isoflavone. Plants can now be genetically engineered to produce isoflavones that provide potential human health benefits and increase disease resistance in plants. Isoflavones can now be produced in transgenic plants species in which isoflavones do not naturally occur, i.e., in species other than legumes. Alternatively, introducing infection-inducible isoflavonoid biosynthesis into non-legumes qualitatively complements these plants' phytoalexin defenses against microbial pathogens, whereas over-expression of the isoflavonoid pathway in legumes quantitatively increases this defense response. Finally, modifying the extend of production of isoflavonoids in legume roots positively impacts nodulation efficiency and therefore plant yield.

IPC 1-7 (main, further and additional classification)

C12N 15/53; A01H 5/00; A01H 5/10; A23L 1/00; C12N 5/10; C12N 9/02; C12N 15/11; C12N 15/82

IPC 8 full level (invention and additional information)

C12N 9/02 (2006.01); C12N 15/53 (2006.01); C12N 15/82 (2006.01)

CPC (invention and additional information)

C12N 9/0077 (2013.01); C12N 15/8242 (2013.01); C12N 15/8243 (2013.01); C12N 15/8261 (2013.01); C12N 15/8279 (2013.01); C07K 2319/00 (2013.01); Y02A 40/146 (2018.01)

Citation (search report)

See references of WO 0053771A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0053771 A1 20000914; AU 3728700 A 20000928; AU 776161 B2 20040826; CA 2362440 A1 20000914; CA 2362440 C 20091208; EP 1161540 A1 20011212; NZ 513992 A 20040326

INPADOC legal status


2011-01-12 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20090708

2007-01-10 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20050517

2005-06-29 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20050517

2001-12-12 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20011008

2001-12-12 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-12-12 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI