Global Patent Index - EP 1161550 A1

EP 1161550 A1 2001-12-12 - TARGET CELL-SPECIFIC, MULTIVALENT PROTEINS (MVP)

Title (en)

TARGET CELL-SPECIFIC, MULTIVALENT PROTEINS (MVP)

Title (de)

ZIELZELLSPEZIFISCHE, MULTIVALENTE PROTEINE (MVP)

Title (fr)

PROTEINES MULTIVALENTES (PMV) SPECIFIQUES A DES CELLULES CIBLES

Publication

EP 1161550 A1 (DE)

Application

EP 00910717 A

Priority

  • DE 19910419 A
  • EP 0001612 W

Abstract (en)

[origin: DE19910419A1] The invention relates to a target cell-specific, multivalent protein (MVP) characterized in being comprised of the following components which are covalently bound to one another: a) a binding structure (a)n specific for the vector; b) a linker (b)m and; d) at least two binding structures (c)o for the target cell, whereby, independent of one another, n=1, m=1-10 and o=2-10. The invention also relates to the production and use of said multivalent protein.

IPC 1-7 (main, further and additional classification)

C12N 15/87; A61K 38/12; A61K 39/00; C07K 14/47; C07K 16/00; C07K 16/46; C12N 15/12; C12N 15/62

IPC 8 full level (invention and additional information)

A61P 37/02 (2006.01); C07K 14/52 (2006.01); C07K 16/08 (2006.01); C07K 16/28 (2006.01); C07K 19/00 (2006.01); C12N 15/12 (2006.01)

CPC (invention and additional information)

C07K 14/52 (2013.01); C07K 16/081 (2013.01); C07K 16/2809 (2013.01); C07K 19/00 (2013.01); C07K 2319/00 (2013.01)

Citation (search report)

See references of WO 0053790A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

DE 19910419 A1 20000921; AU 3282900 A 20000928; EP 1161550 A1 20011212; JP 2002537847 A 20021112; WO 0053790 A1 20000914

INPADOC legal status


2007-08-08 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: KONTERMANN, ROLAND

2007-08-08 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: NETTELBECK, DIRK.M.DRGENE THERAPY CENTER

2007-08-08 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: SEDLACEK, HANS-HARALD

2007-08-08 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: MUELLER, ROLF

2003-07-02 [18W] APPLICATION WITHDRAWN

- Effective date: 20030507

2002-01-16 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: KONTERMANN, ROLAND

2002-01-16 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: NETTELBECK, DIRK.M.DR GENE THERAPY CENTER

2002-01-16 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: SEDLACEK, HANS-HARALD

2002-01-16 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: MUELLER, ROLF

2001-12-12 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20011010

2001-12-12 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-12-12 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI