Global Patent Index - EP 1162961 A2

EP 1162961 A2 2001-12-19 - REGULATION OF HER2/neu ONCONGENE EXPRESSION BY SYNTHETIC POLYAMIDES

Title (en)

REGULATION OF HER2/neu ONCONGENE EXPRESSION BY SYNTHETIC POLYAMIDES

Title (de)

REGULATION DER HER2/NEU ONCOGENE EXPRESSION MITTELS SYNTHETISCHEN POLYAMIDEN

Title (fr)

REGULATION DE L'EXPRESSION ONCONGENE DE HER2/NEU PAR DES POLYAMIDES SYNTHETIQUES

Publication

EP 1162961 A2 (EN)

Application

EP 99969022 A

Priority

  • US 9920840 W
  • US 9990698 P

Abstract (en)

[origin: WO0015242A1] Methods and compositions comprising polyamides capable of binding the minor groove of double-stranded DNA are described for the inhibition or reduction or gene transcription and expression. The polyamides comprise at least four complementary pairs of aromatic carboxamide residues which are selected to specifically contact and/or bind to the nucleotide sequence of a double-stranded DNA target in the promoter region of the target gene. The methods, compositions, and polyamides are disclosed for the inhibition of oncogene transcription and expression as well as the treatment of cancer.

IPC 1-7 (main, further and additional classification)

A61K 31/00

IPC 8 full level (invention and additional information)

A61K 31/785 (2006.01); A61K 31/00 (2006.01); A61K 31/4178 (2006.01); A61K 38/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/566 (2006.01)

CPC (invention and additional information)

A61K 31/00 (2013.01); A61K 31/4178 (2013.01)

Citation (search report)

See references of WO 0015209A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0015242 A1 20000323; AU 6034199 A 20000403; AU 6496599 A 20000403; AU 768405 B2 20031211; CA 2343289 A1 20000323; CA 2344654 A1 20000323; EP 1112080 A1 20010704; EP 1112080 A4 20021024; EP 1162961 A2 20011219; JP 2002524501 A 20020806; JP 2002524525 A 20020806; WO 0015209 A2 20000323; WO 0015209 A3 20000525

INPADOC legal status


2005-04-27 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20041019

2004-05-26 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20040407

2001-12-19 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20010328

2001-12-19 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-12-19 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20010328;LT PAYMENT 20010328;LV PAYMENT 20010328;MK PAYMENT 20010328;RO PAYMENT 20010328;SI PAYMENT 20010328