EP 1163215 A1 20011219 - AMINO-THIO-ACRYLONITRILES AS MEK INHIBITORS
Title (en)
AMINO-THIO-ACRYLONITRILES AS MEK INHIBITORS
Title (de)
AMINO-THIO-ACRYLONITRILE ALS MEK-INHIBITOREN
Title (fr)
AMINO-THIO-ACRYLONITRILES UTILISES COMME INHIBITEURS DES KINASES MEK
Publication
Application
Priority
- US 0007262 W 20000315
- US 12533099 P 19990319
Abstract (en)
[origin: WO0056706A1] This invention relates generally to amino-thio-acrylonitriles of formula (Ia) or (Ib) as MEK inhibitors, pharmaceutical compositions containing the same, and methods of using the same as for treatment and prevention of inflammatory disorders or as an anticancer radiosensitizing agent.
IPC 1-7
C07C 323/60; C07D 213/57; C07D 333/24; C07D 333/34; C07D 207/32; C07D 307/54; A61K 31/277; A61K 31/44; A61K 31/381; A61K 31/40; A61K 31/341; A61P 35/00
IPC 8 full level
A61P 35/00 (2006.01); C07C 323/60 (2006.01); C07D 207/337 (2006.01); C07D 213/57 (2006.01); C07D 307/54 (2006.01); C07D 333/24 (2006.01); C07D 333/34 (2006.01); C07D 207/32 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); C07C 323/60 (2013.01); C07D 207/337 (2013.01); C07D 213/57 (2013.01); C07D 307/54 (2013.01); C07D 333/24 (2013.01); C07D 333/34 (2013.01)
Citation (search report)
See references of WO 0056706A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0056706 A1 20000928; AU 3761400 A 20001009; CA 2362380 A1 20000928; EP 1163215 A1 20011219
DOCDB simple family (application)
US 0007262 W 20000315; AU 3761400 A 20000315; CA 2362380 A 20000315; EP 00916525 A 20000315