Global Patent Index - EP 1163215 A1

EP 1163215 A1 2001-12-19 - AMINO-THIO-ACRYLONITRILES AS MEK INHIBITORS

Title (en)

AMINO-THIO-ACRYLONITRILES AS MEK INHIBITORS

Title (de)

AMINO-THIO-ACRYLONITRILE ALS MEK-INHIBITOREN

Title (fr)

AMINO-THIO-ACRYLONITRILES UTILISES COMME INHIBITEURS DES KINASES MEK

Publication

EP 1163215 A1 (EN)

Application

EP 00916525 A

Priority

  • US 0007262 W
  • US 12533099 P

Abstract (en)

[origin: WO0056706A1] This invention relates generally to amino-thio-acrylonitriles of formula (Ia) or (Ib) as MEK inhibitors, pharmaceutical compositions containing the same, and methods of using the same as for treatment and prevention of inflammatory disorders or as an anticancer radiosensitizing agent.

IPC 1-7 (main, further and additional classification)

C07C 323/60; A61K 31/277; A61K 31/341; A61K 31/381; A61K 31/40; A61K 31/44; A61P 35/00; C07D 207/32; C07D 213/57; C07D 307/54; C07D 333/24; C07D 333/34

IPC 8 full level (invention and additional information)

A61P 35/00 (2006.01); C07C 323/60 (2006.01); C07D 207/337 (2006.01); C07D 213/57 (2006.01); C07D 307/54 (2006.01); C07D 333/24 (2006.01); C07D 333/34 (2006.01); C07D 207/32 (2006.01)

CPC (invention and additional information)

C07D 207/337 (2013.01); C07C 323/60 (2013.01); C07D 213/57 (2013.01); C07D 307/54 (2013.01); C07D 333/24 (2013.01); C07D 333/34 (2013.01)

Citation (search report)

See references of WO 0056706A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0056706 A1 20000928; AU 3761400 A 20001009; CA 2362380 A1 20000928; EP 1163215 A1 20011219

INPADOC legal status


2003-04-02 [18R] REFUSED

- Effective date: 20021101

2002-10-30 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: BRISTOL-MYERS SQUIBB PHARMA COMPANY

2002-06-12 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020502

2001-12-19 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20010822

2001-12-19 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-12-19 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: LT PAYMENT 20010822;LV PAYMENT 20010822;RO PAYMENT 20010822;SI PAYMENT 20010822