Title (en)

COMPOSITIONS, KITS, AND METHODS RELATING TO THE HUMAN FEZ1 GENE, A NOVEL TUMOR SUPPRESSOR GENE

Title (de)

ZUSAMMENSETZUNGEN, KITS UND VERFAHREN IN VERBINDUNG MIT DEM MENSCHLICHEN FEZ1-GEN, EINEM NEUEN TUMORSUPRESSORGEN

Title (fr)

COMPOSITIONS, KITS ET PROCEDES CONCERNANT LE GENE FEZ1 DE L'HOMME, NOUVEAU GENE SUPPRESSEUR DES TUMEURS

Publication

EP 1163252 A2 20011219 (EN)

Application

EP 00912007 A 20000225

Priority

• US 0004950 W 20000225
• US 12153799 P 19990225

Abstract (en)

[origin: WO0050565A2] The invention relates to isolated polynucleotides homologous with a portion of one strand of the human tumor suppressor gene, FEZ1, and to the tumor suppressor protein encoded thereby, Fez1. The polynucleotides are useful, for example, as probes, primers, portions of expression vectors, and the like. The invention also includes diagnostic, therapeutic, cell proliferation enhancement, and screening methods which involve these polynucleotides and protein. The invention further includes kits useful for performing the methods of the invention.

IPC 1-7

C07K 14/47

IPC 8 full level

A01K 67/027 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C07K 14/47 (2006.01); C07K 14/82 (2006.01); C07K 16/32 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01); G01N 33/574 (2006.01); G01N 37/00 (2006.01)

CPC (source: EP)

A61P 35/00 (2017.12); C07K 14/4703 (2013.01); A61K 38/00 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0050565 A2 20000831; WO 0050565 A3 20001207; CA 2361396 A1 20000831; EP 1163252 A2 20011219; EP 1163252 A4 20040407; JP 2003508011 A 20030304

DOCDB simple family (application)

US 0004950 W 20000225; CA 2361396 A 20000225; EP 00912007 A 20000225; JP 2000601129 A 20000225