EP 1163252 A4 20040407 - COMPOSITIONS, KITS, AND METHODS RELATING TO THE HUMAN FEZ1 GENE, A NOVEL TUMOR SUPPRESSOR GENE
Title (en)
COMPOSITIONS, KITS, AND METHODS RELATING TO THE HUMAN FEZ1 GENE, A NOVEL TUMOR SUPPRESSOR GENE
Title (de)
ZUSAMMENSETZUNGEN, KITS UND VERFAHREN IN VERBINDUNG MIT DEM MENSCHLICHEN FEZ1-GEN, EINEM NEUEN TUMORSUPRESSORGEN
Title (fr)
COMPOSITIONS, KITS ET PROCEDES CONCERNANT LE GENE FEZ1 DE L'HOMME, NOUVEAU GENE SUPPRESSEUR DES TUMEURS
Publication
Application
Priority
- US 0004950 W 20000225
- US 12153799 P 19990225
Abstract (en)
[origin: WO0050565A2] The invention relates to isolated polynucleotides homologous with a portion of one strand of the human tumor suppressor gene, FEZ1, and to the tumor suppressor protein encoded thereby, Fez1. The polynucleotides are useful, for example, as probes, primers, portions of expression vectors, and the like. The invention also includes diagnostic, therapeutic, cell proliferation enhancement, and screening methods which involve these polynucleotides and protein. The invention further includes kits useful for performing the methods of the invention.
IPC 1-7
IPC 8 full level
A01K 67/027 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C07K 14/47 (2006.01); C07K 14/82 (2006.01); C07K 16/32 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01); G01N 33/574 (2006.01); G01N 37/00 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); C07K 14/4703 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
- [E] WO 0155300 A2 20010802 - HUMAN GENOME SCIENCES INC [US], et al
- [E] WO 0155448 A1 20010802 - HUMAN GENOME SCIENCES INC [US], et al
- [X] DATABASE EMBL [online] 1 July 1998 (1998-07-01), "ox62e04.x1 Soares_NhHMPu_S1 Homo sapiens cDNA clone IMAGE:1660926 3', mRNA sequence", XP002266794, Database accession no. AI042490
- [PX] ISHII H ET AL: "The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. UNITED STATES 30 MAR 1999, vol. 96, no. 7, 30 March 1999 (1999-03-30), pages 3928 - 3933, XP002266793, ISSN: 0027-8424
- See references of WO 0050565A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0050565 A2 20000831; WO 0050565 A3 20001207; CA 2361396 A1 20000831; EP 1163252 A2 20011219; EP 1163252 A4 20040407; JP 2003508011 A 20030304
DOCDB simple family (application)
US 0004950 W 20000225; CA 2361396 A 20000225; EP 00912007 A 20000225; JP 2000601129 A 20000225