Global Patent Index - EP 1163327 A1

EP 1163327 A1 2001-12-19 - HUMAN PROTEIN KINASE B GAMMA POLYPEPTIDES AND A METHOD FOR DISRUPTING PROTEIN KINASE B GAMMA IN A NON-HUMAN

Title (en)

HUMAN PROTEIN KINASE B GAMMA POLYPEPTIDES AND A METHOD FOR DISRUPTING PROTEIN KINASE B GAMMA IN A NON-HUMAN

Title (de)

POLYPEPTIDE DER HUMANEN PROTEINKINASE GAMMA UND VERFAHREN ZUR UNTERBRECHUNG DER PROTEINKINASE GAMMA IN NICHT-MENSCHLICHEN ORGANISMEN

Title (fr)

POLYPEPTIDES DE PROTEINE-KINASE B GAMMA HUMAINE ET PROCEDE DE DISLOCATION DE LA PROTEINE-KINASE B GAMMA CHEZ UN SUJET NON HUMAIN

Publication

EP 1163327 A1 (EN)

Application

EP 00921244 A

Priority

  • SE 0000571 W
  • SE 9901115 A

Abstract (en)

[origin: WO0058446A1] The present invention relates to human protein kinase B gamma polypeptides and to nucleic acid molecules coding for such polypeptides. The invention further relates to vectors and cells comprising said nucleic acid molecules, as well as to methods for screening test compounds which affect the insulin signaling pathway. In contrast to the previously known protein kinase B gamma from rat brain, the human protein kinase B gamma polypeptides comprise two activating phosphorylation residues; Thr<305> and Ser<472>.

[origin: WO0058446A1] The present invention relates to human protein kinase B gamma polypeptides and to nucleic acid molecules coding for such polypeptides. The invention further relates to vectors and cells comprising said nucleic acid molecules, as well as to methods for screening test compounds which affect the insulin signaling pathway. In contrast to the previously known protein kinase B gamma from rat brain, the human protein kinase B gamma polypeptides comprise two activating phosphorylation residues; Thr<305> and Ser<472>.

IPC 1-7 (main, further and additional classification)

C12N 9/12; A01K 67/027; A61K 48/00; C12N 15/00; C12Q 1/48

IPC 8 full level (invention and additional information)

A01K 67/027 (2006.01); C07K 16/40 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/12 (2006.01); C12N 15/09 (2006.01); C12Q 1/48 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01); G01N 33/573 (2006.01)

CPC (invention and additional information)

C12N 9/1205 (2013.01); A01K 2217/075 (2013.01)

Citation (search report)

See references of WO 0058446A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0058446 A1 20001005; AU 4158100 A 20001016; CA 2368379 A1 20001005; EP 1163327 A1 20011219; JP 2002539823 A 20021126; SE 9901115 D0 19990325

INPADOC legal status


2004-03-10 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20030904

2003-06-04 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030423

2002-03-06 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: BIOVITRUM AB

2001-12-19 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20011004

2001-12-19 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-12-19 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI