Global Patent Index - EP 1163336 A2

EP 1163336 A2 2001-12-19 - VERTEBRATE PROTEIN SLIT, DNA SEQUENCE ENCODING IT AND USES THEREOF

Title (en)

VERTEBRATE PROTEIN SLIT, DNA SEQUENCE ENCODING IT AND USES THEREOF

Title (de)

SLIT PROTEIN AUS WIRBELTIEREN, KODIERENDE DNA SEQUENZ UND ENTSPRECHENDE VERWENDUNGEN

Title (fr)

SEQUENCE D'ADN ET PROTEINE SLIT DE VERTEBRE, ET UTILISATIONS ASSOCIEES

Publication

EP 1163336 A2 (EN)

Application

EP 00916449 A

Priority

  • US 0007040 W
  • US 12476799 P

Abstract (en)

[origin: WO0055321A2] Polynucleotides that encode the Xenopus slit protein along with the deduced amino acid sequence of the Xenopus slit protein are given. Recombinant polynucleotides, vectors and transformed cells containing the slit polynucleotide are disclosed. Methods for production of slit proteins, pharmaceutical compounds containing slit protein and therapeutic uses for slit protein are also given. Methods for the repulsive guidance of nerve axon growth and inhibition of cell migration using slit are provided. Methods of stimulating cell proliferation using slit are given, along with methods and compositions for reducing the use of serum in cell culture by the use of slit.

IPC 1-7 (main, further and additional classification)

C12N 15/12; A61K 38/18; C07K 14/475

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61P 1/00 (2006.01); A61P 9/00 (2006.01); A61P 11/06 (2006.01); A61P 13/12 (2006.01); A61P 17/02 (2006.01); A61P 19/02 (2006.01); A61P 25/00 (2006.01); A61P 25/28 (2006.01); A61P 31/18 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 37/06 (2006.01); A61P 43/00 (2006.01); C07K 14/47 (2006.01); C07K 14/475 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/02 (2006.01); C12N 5/10 (2006.01); C12N 15/12 (2006.01); C12P 21/02 (2006.01)

CPC (invention and additional information)

C07K 14/475 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

See references of WO 0055321A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0055321 A2 20000921; WO 0055321 A3 20010628; WO 0055321 B1 20010719; AU 3755100 A 20001004; CA 2365214 A1 20000921; EP 1163336 A2 20011219; JP 2002538823 A 20021119

INPADOC legal status


2005-05-25 [18W] APPLICATION WITHDRAWN

- Effective date: 20050401

2001-12-19 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20011010

2001-12-19 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-12-19 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI