EP 1163356 A1 20011219 - RETROVIRAL VECTORS COMPRISING FUNCTIONAL AND NON-FUNCTIONAL SPLICE DONOR AND SPLICE ACCEPTOR SITES
Title (en)
RETROVIRAL VECTORS COMPRISING FUNCTIONAL AND NON-FUNCTIONAL SPLICE DONOR AND SPLICE ACCEPTOR SITES
Title (de)
RETROVIRALE VEKTOREN, DIE FUNKTIONELLE UND NICHT-FUNKTIONELLE SPLICE-DONOR- UND SPLICE-AKZEPTOR-STELLEN ENTHALTEN
Title (fr)
VECTEURS RETROVIRAUX COMPORTANT DES SITES DONNEURS ET ACCEPTEURS D'EPISSURE, FONCTIONNELS ET NON FONCTIONNELS
Publication
Application
Priority
- GB 0001091 W 20000322
- GB 9906615 A 19990322
Abstract (en)
[origin: WO0056910A1] A retroviral vector comprises a functional splice donor site (FSDS) and a functional splice acceptor (FSAS) site; wherein the FSDS and the FSAS flank a first nucleotide sequence of interest (NOI); wherein the FSDS is upstream of the FSAS; wherein the retroviral vector is derived from a retroviral pro-vector; wherein the retroviral pro-vector comprises a first nucleotide sequence (NS) capable of yielding the functional splice donor site (FSDS); a second NS capable of yielding the functional splice acceptor site (FSAS); a third NS capable of yielding a non-functional splice donor site (NFSDS); a fourth NS capable of yielding a non-functional splice site (NFSS); wherein the first NS is downstream of the second NS and wherein the third NS and fourth NS are upstream of the second NS; such that after reverse transcription of the retroviral pro-vector at a desired target site the retroviral vector is capable of being spliced.
IPC 1-7
C12N 15/867; C12N 15/861; C12N 5/10; C12N 7/01; A61K 48/00; C12N 9/12
IPC 8 full level
C12N 15/09 (2006.01); A61K 35/76 (2006.01); A61K 48/00 (2006.01); A61P 1/00 (2006.01); A61P 1/02 (2006.01); A61P 1/14 (2006.01); A61P 1/16 (2006.01); A61P 5/00 (2006.01); A61P 7/02 (2006.01); A61P 7/04 (2006.01); A61P 9/00 (2006.01); A61P 9/10 (2006.01); A61P 11/02 (2006.01); A61P 11/06 (2006.01); A61P 13/12 (2006.01); A61P 15/00 (2006.01); A61P 17/00 (2006.01); A61P 17/06 (2006.01); A61P 19/02 (2006.01); A61P 19/10 (2006.01); A61P 25/00 (2006.01); A61P 25/06 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01); A61P 27/00 (2006.01); A61P 29/00 (2006.01); A61P 31/00 (2006.01); A61P 31/18 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); A61P 37/06 (2006.01); A61P 43/00 (2006.01); C12N 5/10 (2006.01); C12N 7/01 (2006.01); C12N 15/861 (2006.01); C12N 15/867 (2006.01)
CPC (source: EP KR)
A61P 1/00 (2017.12 - EP); A61P 1/02 (2017.12 - EP); A61P 1/14 (2017.12 - EP); A61P 1/16 (2017.12 - EP); A61P 5/00 (2017.12 - EP); A61P 7/02 (2017.12 - EP); A61P 7/04 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 11/02 (2017.12 - EP); A61P 11/06 (2017.12 - EP); A61P 13/12 (2017.12 - EP); A61P 15/00 (2017.12 - EP); A61P 17/00 (2017.12 - EP); A61P 17/06 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 19/10 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/06 (2017.12 - EP); A61P 25/16 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 27/00 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 31/00 (2017.12 - EP); A61P 31/18 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 37/00 (2017.12 - EP); A61P 37/06 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C12N 15/86 (2013.01 - EP); C12N 15/867 (2013.01 - KR); C12N 2710/10344 (2013.01 - EP); C12N 2740/15043 (2013.01 - EP); C12N 2800/40 (2013.01 - EP); C12N 2830/002 (2013.01 - EP); C12N 2830/15 (2013.01 - EP); C12N 2830/42 (2013.01 - EP); C12N 2830/50 (2013.01 - EP); C12N 2840/20 (2013.01 - EP); C12N 2840/203 (2013.01 - EP); C12N 2840/44 (2013.01 - EP)
Citation (search report)
See references of WO 0056910A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0056910 A1 20000928; AU 3312800 A 20001009; CA 2367488 A1 20000928; CN 1344326 A 20020410; EP 1163356 A1 20011219; GB 0120709 D0 20011017; GB 2362886 A 20011205; GB 9906615 D0 19990519; JP 2002539797 A 20021126; KR 20020003215 A 20020110; ZA 200106031 B 20020918
DOCDB simple family (application)
GB 0001091 W 20000322; AU 3312800 A 20000322; CA 2367488 A 20000322; CN 00805182 A 20000322; EP 00911135 A 20000322; GB 0120709 A 20000322; GB 9906615 A 19990322; JP 2000606769 A 20000322; KR 20017012059 A 20010921; ZA 200106031 A 20010723