EP 1165604 A2 20020102 - PROTEINS RELATED TO NEURONAL REGENERATION AND USES THEREOF
Title (en)
PROTEINS RELATED TO NEURONAL REGENERATION AND USES THEREOF
Title (de)
PROTEINE, DIE MIT NEURONALER REGENERIERUNG ZUSAMMENHANGEN, UND IHRE VERWENDUNGEN
Title (fr)
PROTEINES ASSOCIEES A LA REGENERATION NEURONALE ET LEUR UTILISATION
Publication
Application
Priority
- CA 0000126 W 20000211
- US 11983599 P 19990212
Abstract (en)
[origin: WO0047615A2] The invention provides a method for stimulating nerve growth, which also includes nerve regeneration, by contacting nerve cells with human Neural Plakophilin Related Armadillo Protein (hNPRAP). In a specific embodiment, hNPRAP causes the development of numerous long, cellular extensions, which are similar to axonal sprouting observed during neuronal regeneration and synapse formation. The invention further relates to pharmaceutical compositions comprising an hNPRAP, or alternatively a gene therapy vector that expresses an hNPRAP. Also provided are methods for identifying substances that modulate expression of hNPRAP.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61P 25/00 (2006.01); A61P 25/28 (2006.01); A61P 43/00 (2006.01); C07K 14/48 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01)
CPC (source: EP)
A61P 25/00 (2017.12); A61P 25/28 (2017.12); A61P 43/00 (2017.12); C07K 14/48 (2013.01)
Citation (search report)
See references of WO 0047615A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0047615 A2 20000817; WO 0047615 A3 20001130; AU 2652600 A 20000829; CA 2361034 A1 20000817; EP 1165604 A2 20020102; JP 2002541060 A 20021203; MX PA01007944 A 20030910
DOCDB simple family (application)
CA 0000126 W 20000211; AU 2652600 A 20000211; CA 2361034 A 20000211; EP 00904750 A 20000211; JP 2000598531 A 20000211; MX PA01007944 A 20000211