Global Patent Index - EP 1166116 A1

EP 1166116 A1 20020102 - MINIATURIZED CELL ARRAY METHODS AND APPARATUS FOR CELL-BASED SCREENING

Title (en)

MINIATURIZED CELL ARRAY METHODS AND APPARATUS FOR CELL-BASED SCREENING

Title (de)

METHODEN ZUR MINIATURISIERTEN ZELLENANORDNUNG UND AUF ZELLEN BASIERTES SCREENING GERÄT

Title (fr)

JEUX ORDONNES D'ECHANTILLONS MINIATURISES ET APPAREIL POUR CRIBLAGE SUR UNE BASE CELLULAIRE

Publication

EP 1166116 A1 20020102 (EN)

Application

EP 00920037 A 20000331

Priority

  • US 0008767 W 20000331
  • US 12733999 P 19990401
  • US 13811999 P 19990607

Abstract (en)

[origin: WO0060356A1] The present invention describes novel methods for making a substrate for selective cell patterning, and the substrates themselves, wherein the method comprises contacting reactive hydroxyl groups on the surface of a substrate with a hydroxyl-reactive bifunctional molecule to form a monolayer, and using stencils to deposit cell repulsive or cell adhesive moieties in controlled locations on the cell culture substrate. Methods comprising selective differentiation of stem cells to create tissue specific and organ-specific cell substrates, as well as the cell substrates themselves are also provided.

IPC 1-7

G01N 33/543

IPC 8 full level

G01N 33/53 (2006.01); B01J 19/00 (2006.01); C12M 1/34 (2006.01); C12M 3/00 (2006.01); C12Q 1/02 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/543 (2006.01); G01N 37/00 (2006.01); C40B 40/10 (2006.01); C40B 60/14 (2006.01)

CPC (source: EP)

B01J 19/0046 (2013.01); B82Y 5/00 (2013.01); B82Y 30/00 (2013.01); G01N 33/543 (2013.01); G01N 33/54353 (2013.01); B01J 2219/00317 (2013.01); B01J 2219/00367 (2013.01); B01J 2219/00427 (2013.01); B01J 2219/0043 (2013.01); B01J 2219/00585 (2013.01); B01J 2219/00596 (2013.01); B01J 2219/00605 (2013.01); B01J 2219/0061 (2013.01); B01J 2219/00612 (2013.01); B01J 2219/00617 (2013.01); B01J 2219/00619 (2013.01); B01J 2219/00621 (2013.01); B01J 2219/0063 (2013.01); B01J 2219/00635 (2013.01); B01J 2219/00637 (2013.01); B01J 2219/00644 (2013.01); B01J 2219/00659 (2013.01); B01J 2219/00725 (2013.01); C40B 40/10 (2013.01); C40B 60/14 (2013.01)

Citation (search report)

See references of WO 0060356A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0060356 A1 20001012; AT E242486 T1 20030615; AU 4063700 A 20001023; CA 2368773 A1 20001012; DE 60003171 D1 20030710; DE 60003171 T2 20040408; EP 1166116 A1 20020102; EP 1166116 B1 20030604; IL 145222 A0 20020630; JP 2002541458 A 20021203

DOCDB simple family (application)

US 0008767 W 20000331; AT 00920037 T 20000331; AU 4063700 A 20000331; CA 2368773 A 20000331; DE 60003171 T 20000331; EP 00920037 A 20000331; IL 14522200 A 20000331; JP 2000609795 A 20000331