Global Patent Index - EP 1169297 A4

EP 1169297 A4 2002-09-18 - METHOD FOR THE PRODUCTION OF SERINOL

Title (en)

METHOD FOR THE PRODUCTION OF SERINOL

Title (de)

VERFAHREN ZUR HERSTELLUNG VON SERINOL

Title (fr)

METHODE DE PRODUCTION DE SERINOL

Publication

EP 1169297 A4 (EN)

Application

EP 00911440 A

Priority

  • KR 0000192 W
  • KR 19990007754 A

Abstract (en)

[origin: WO0053567A1] Disclosed is a method for preparing serinol (2-amino-1,3-proanediol). From nitromethane, para-formaldehyde and sodium hydroxide, 1-nitro-1,3-propanediol sodium salt is prepared as a medical intermediate. In a fixed bed, this intermediate is allowed to undergo the continuous hydrogenation of 2-nitro-1,3-propanediol sodium salt and methanol as shown in reaction (I). In addition to being simple, the method is economically favorable and affords the high yield and high purity of serinol.

[origin: WO0053567A1] Disclosed is a method for preparing serinol (2-amino-1,3-proanediol). From nitromethane, para-formaldehyde and sodium hydroxide, 1-nitro-1,3-propanediol sodium salt is prepared as a medical intermediate. In a fixed bed, this intermediate is allowed to undergo the continuous hydrogenation of 2-nitro-1,3-propanediol sodium salt and methanol as shown in reaction (I). In addition to being simple, the method is economically favorable and affords the high yield and high purity of serinol.

IPC 1-7 (main, further and additional classification)

C07C 215/10; C07C 205/14

IPC 8 full level (invention and additional information)

B01J 23/44 (2006.01); B01J 23/46 (2006.01); C07B 61/00 (2006.01); C07C 205/15 (2006.01); C07C 213/02 (2006.01); C07C 215/10 (2006.01)

CPC (invention and additional information)

C07C 213/02 (2013.01); C07C 201/12 (2013.01)

Combination set (CPC)

  1. C07C 213/02 + C07C 215/10
  2. C07C 201/12 + C07C 205/15

Citation (search report)

  • No further relevant documents disclosed
  • See also references of WO 0053567A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0053567 A1 20000914; WO 0053567 A8 20010412; AT 277886 T 20041015; DE 60014342 D1 20041104; DE 60014342 T2 20051229; EP 1169297 A1 20020109; EP 1169297 A4 20020918; EP 1169297 B1 20040929; ES 2228477 T3 20050416; JP 2002539109 A 20021119; KR 100286570 B1 20010315; KR 20000059869 A 20001016; PT 1169297 E 20050228; US 6509504 B1 20030121

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