Global Patent Index - EP 1169323 A1

EP 1169323 A1 20020109 - BETA-LACTAMASE INHIBITING COMPOUNDS

Title (en)

BETA-LACTAMASE INHIBITING COMPOUNDS

Title (de)

BETA-LACTAMASE HEMMENDE VERBINDUNGEN

Title (fr)

COMPOSES INHIBANT LA BETA-LACTAMASE

Publication

EP 1169323 A1 20020109 (EN)

Application

EP 00922157 A 20000414

Priority

  • US 0009929 W 20000414
  • US 12948299 P 19990415

Abstract (en)

[origin: WO0063213A1] The invention provides compounds of formula (I) and (IV), wherein R1-R11 and A have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting beta -lactamase enzymes, for enhancing the activity of beta -lactam antibiotics, and for treating beta -lactam resistant bacterial infections in a mammal. The invention also provides pharmaceutical compositions, processes for preparing compounds of formula (I) and (IV), and novel intermediates useful for the synthesis of compounds of formula (I) and (IV).

IPC 1-7

C07D 501/00; A61K 31/545; A61P 31/00

IPC 8 full level

A61K 31/545 (2006.01); A61K 31/546 (2006.01); A61P 31/00 (2006.01); A61P 31/04 (2006.01); C07D 501/00 (2006.01)

CPC (source: EP)

A61P 31/00 (2018.01); A61P 31/04 (2018.01); C07D 501/00 (2013.01)

Citation (search report)

See references of WO 0063213A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0063213 A1 20001026; AT 330960 T 20060715; AU 4238600 A 20001102; AU 773013 B2 20040513; CA 2371389 A1 20001026; DE 60029023 D1 20060803; DE 60029023 T2 20070118; EP 1169323 A1 20020109; JP 2002542249 A 20021210; MX PA01010409 A 20031211

DOCDB simple family (application)

US 0009929 W 20000414; AT 03015238 T 20000414; AU 4238600 A 20000414; CA 2371389 A 20000414; DE 60029023 T 20000414; EP 00922157 A 20000414; JP 2000612303 A 20000414; MX PA01010409 A 20000414