EP 1169323 A1 20020109 - BETA-LACTAMASE INHIBITING COMPOUNDS
Title (en)
BETA-LACTAMASE INHIBITING COMPOUNDS
Title (de)
BETA-LACTAMASE HEMMENDE VERBINDUNGEN
Title (fr)
COMPOSES INHIBANT LA BETA-LACTAMASE
Publication
Application
Priority
- US 0009929 W 20000414
- US 12948299 P 19990415
Abstract (en)
[origin: WO0063213A1] The invention provides compounds of formula (I) and (IV), wherein R1-R11 and A have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting beta -lactamase enzymes, for enhancing the activity of beta -lactam antibiotics, and for treating beta -lactam resistant bacterial infections in a mammal. The invention also provides pharmaceutical compositions, processes for preparing compounds of formula (I) and (IV), and novel intermediates useful for the synthesis of compounds of formula (I) and (IV).
IPC 1-7
IPC 8 full level
A61K 31/545 (2006.01); A61K 31/546 (2006.01); A61P 31/00 (2006.01); A61P 31/04 (2006.01); C07D 501/00 (2006.01)
CPC (source: EP)
A61P 31/00 (2018.01); A61P 31/04 (2018.01); C07D 501/00 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0063213 A1 20001026; AT E330960 T1 20060715; AU 4238600 A 20001102; AU 773013 B2 20040513; CA 2371389 A1 20001026; DE 60029023 D1 20060803; DE 60029023 T2 20070118; EP 1169323 A1 20020109; JP 2002542249 A 20021210; MX PA01010409 A 20031211
DOCDB simple family (application)
US 0009929 W 20000414; AT 03015238 T 20000414; AU 4238600 A 20000414; CA 2371389 A 20000414; DE 60029023 T 20000414; EP 00922157 A 20000414; JP 2000612303 A 20000414; MX PA01010409 A 20000414