EP 1169483 B1 20050803 - VARIATION IN DRUG RESPONSE RELATED TO POLYMORPHISMS IN BETA2- ADRENERGIC RECEPTOR
Title (en)
VARIATION IN DRUG RESPONSE RELATED TO POLYMORPHISMS IN BETA2- ADRENERGIC RECEPTOR
Title (de)
VARIATIONEN IN DER ARZNEIMITTELANTWORT IN ZUSAMMENHANG MIT POLYMORPHISMEN DES ADRENERGEN REZEPTORS BETA 2
Title (fr)
VARIATION DE LA REPONSE A UN MEDICAMENT LIEE AUX POLYMORPHISMES DU RECEPTEUR ADRENERGIQUE BETA-2
Publication
Application
Priority
- US 0006502 W 20000310
- US 12406099 P 19990312
Abstract (en)
[origin: WO0106910A2] A method for predicting an individual's response to the ss-agonists salmeterol, albuterol, metaproterenol, terbutaline and formoterol is disclosed. Individuals expressing the Ile164 ss2AR variant are likely to exhibit a reduced response as compared to individuals expressing the Thr164 ss2AR variant. The method is useful for making treatment decisions for patients suffering from asthma and chronic obstructive pulmonary diseases.
IPC 1-7
IPC 8 full level
C07K 14/705 (2006.01); C12Q 1/68 (2006.01); C12Q 1/6883 (2018.01)
CPC (source: EP)
C07K 14/70571 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0106910 A2 20010201; WO 0106910 A3 20010927; AT E301202 T1 20050815; AU 1750701 A 20010213; AU 776319 B2 20040902; DE 60021718 D1 20050908; EP 1169483 A2 20020109; EP 1169483 A4 20030312; EP 1169483 B1 20050803
DOCDB simple family (application)
US 0006502 W 20000310; AT 00980212 T 20000310; AU 1750701 A 20000310; DE 60021718 T 20000310; EP 00980212 A 20000310