EP 1171118 A2 20020116 - METHODS AND COMPOSITIONS FOR ENHANCING DELIVERY OF THERAPEUTIC AGENTS TO TISSUES
Title (en)
METHODS AND COMPOSITIONS FOR ENHANCING DELIVERY OF THERAPEUTIC AGENTS TO TISSUES
Title (de)
VERFAHREN UND ARZNEIMITTEL ZUR ERHÖHUNG DER WIRKSTOFFVERABREICHUNG AN GEWEBE
Title (fr)
METHODES ET COMPOSITIONS AMELIORANT LA DIFFUSION D'AGENTS THERAPEUTIQUES A L'INTERIEUR DE TISSUS
Publication
Application
Priority
- US 0009329 W 20000407
- US 12867499 P 19990409
Abstract (en)
[origin: WO0061141A2] The invention, at least in part, is directed to methods for enhancing delivery of therapeutic agents, such as macromolecules and drugs, into the interior of tissues, such as solid tissues or tumors. The method initially uses an apoptosis inducing agent, such as paclitaxel, in doses which create channels within the tissues, and enhance the penetration of therapeutic agents to the interior of the tissue. Current methods of treating tissues are often not effective because the therapeutic agents are not delivered to the interior of the tissue. By using the methods and the compositions of the current invention, therapeutic agents can be delivered to the interior of the tissue.
IPC 1-7
IPC 8 full level
A61K 9/10 (2006.01); A61K 9/50 (2006.01); A61K 9/51 (2006.01); A61K 31/337 (2006.01); A61K 31/704 (2006.01); A61K 31/711 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP)
A61K 9/5153 (2013.01); A61P 35/00 (2017.12); A61P 43/00 (2017.12)
Citation (search report)
See references of WO 0061141A2
Citation (examination)
- WO 9513798 A1 19950526 - CANCER RES INST INC [AU], et al
- WO 9843618 A2 19981008 - NEORX CORP [US]
- WO 9323014 A1 19931125 - MARTIN DANIEL S [US], et al
- WO 9858927 A1 19981230 - BAKER NORTON PHARMA [US]
- SPENCER C.M. ET AL: "PACLITAXEL A REVIEW OF ITS PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES AND THERAPEUTIC POTENTIAL IN THE TREATMENT OF CANCER", DRUGS, ADIS INTERNATIONAL LTD, NZ LNKD- DOI:10.2165/00003495-199448050-00009, vol. 48, no. 5, 1 January 1994 (1994-01-01), pages 794 - 847, XP008011776, ISSN: 0012-6667
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0061141 A2 20001019; WO 0061141 A3 20010301; AU 4214200 A 20001114; AU 777620 B2 20041021; CA 2369263 A1 20001019; EP 1171118 A2 20020116; JP 2003524624 A 20030819
DOCDB simple family (application)
US 0009329 W 20000407; AU 4214200 A 20000407; CA 2369263 A 20000407; EP 00921881 A 20000407; JP 2000610474 A 20000407