Global Patent Index - EP 1171118 A2

EP 1171118 A2 20020116 - METHODS AND COMPOSITIONS FOR ENHANCING DELIVERY OF THERAPEUTIC AGENTS TO TISSUES

Title (en)

METHODS AND COMPOSITIONS FOR ENHANCING DELIVERY OF THERAPEUTIC AGENTS TO TISSUES

Title (de)

VERFAHREN UND ARZNEIMITTEL ZUR ERHÖHUNG DER WIRKSTOFFVERABREICHUNG AN GEWEBE

Title (fr)

METHODES ET COMPOSITIONS AMELIORANT LA DIFFUSION D'AGENTS THERAPEUTIQUES A L'INTERIEUR DE TISSUS

Publication

EP 1171118 A2 20020116 (EN)

Application

EP 00921881 A 20000407

Priority

  • US 0009329 W 20000407
  • US 12867499 P 19990409

Abstract (en)

[origin: WO0061141A2] The invention, at least in part, is directed to methods for enhancing delivery of therapeutic agents, such as macromolecules and drugs, into the interior of tissues, such as solid tissues or tumors. The method initially uses an apoptosis inducing agent, such as paclitaxel, in doses which create channels within the tissues, and enhance the penetration of therapeutic agents to the interior of the tissue. Current methods of treating tissues are often not effective because the therapeutic agents are not delivered to the interior of the tissue. By using the methods and the compositions of the current invention, therapeutic agents can be delivered to the interior of the tissue.

IPC 1-7

A61K 31/337; A61K 9/51; A61K 31/704; A61P 35/00

IPC 8 full level

A61K 9/10 (2006.01); A61K 9/50 (2006.01); A61K 9/51 (2006.01); A61K 31/337 (2006.01); A61K 31/704 (2006.01); A61K 31/711 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01)

CPC (source: EP)

A61K 9/5153 (2013.01); A61P 35/00 (2018.01); A61P 43/00 (2018.01)

Citation (search report)

See references of WO 0061141A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0061141 A2 20001019; WO 0061141 A3 20010301; AU 4214200 A 20001114; AU 777620 B2 20041021; CA 2369263 A1 20001019; EP 1171118 A2 20020116; JP 2003524624 A 20030819

DOCDB simple family (application)

US 0009329 W 20000407; AU 4214200 A 20000407; CA 2369263 A 20000407; EP 00921881 A 20000407; JP 2000610474 A 20000407