EP 1171448 A2 20020116 - MACROLIDE ANTIINFECTIVE AGENTS
Title (en)
MACROLIDE ANTIINFECTIVE AGENTS
Title (de)
ANTIINFEKTIÖSE MAKROLIDDERIVATE
Title (fr)
AGENTS ANTI-INFECTIEUX MACROLIDE
Publication
Application
Priority
- US 0009915 W 20000414
- US 12972999 P 19990416
- US 14017599 P 19990618
- US 17215999 P 19991217
- US 17215499 P 19991217
- US 17380599 P 19991230
- US 17380499 P 19991230
- US 55116200 A 20000414
Abstract (en)
[origin: CA2369886A1] Compounds of formula (1), (2) or (3) or the 10,11-anhydro forms thereof, wherein Ra is H or OH; Rb is H or halogen; Rc is H or a protecting group; Rd is methyl; unsubstituted alkyl(3-10C); substituted alkyl(1-10C); substituted or unsubstituted alkenyl(2-10C) or substituted or unsubstituted alkynyl(2- 10C); substituted or unsubstituted aryl(4-14C); substituted or unsubstituted arylalkyl(5-20C); substituted or unsubstituted arylalkenyl(5-20C); substitut ed or unsubstituted arylalkynyl(5-20C); substituted or unsubstituted amidoarylalkyl(5-20C); substituted or unsubstituted amidoarylalkenyl(5-20C); or substituted or unsubstituted amidoarylalkynyl(5-20C); Re is H or a protecting group or is mono- or disubstituted amino carbonyl; Rf is H; substituted or unsubstituted alkyl(1-10C), substituted or unsubstituted alkenyl(1-10C); substituted or unsubstituted alkynyl(1-10C); substituted or unsubstituted aryl(4-14C); substituted or unsubstituted arylalkyl(5-20C); or - ORf may be replaced by -H; one of Z and Y is H and the other is OH or protected OH, or is amino, mono- or dialkyl-amino, protected amino, or an aminoheterocycle or Z and Y together are =O, =NOH or a derivatized oxime; including any pharmaceutically acceptable salts thereof and any stereoisomer ic forms and mixtures of stereoisomeric forms thereof, are antimicrobial agents .
IPC 1-7
IPC 8 full level
C07H 17/08 (2006.01); A61K 31/70 (2006.01); A61K 31/7048 (2006.01); A61P 31/00 (2006.01)
IPC 8 main group level
C07H (2006.01)
CPC (source: EP)
Y02P 20/55 (2015.11)
Citation (search report)
See references of WO 0063225A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
BR 0010681 A 20020205; CA 2369886 A1 20001026; CN 1636008 A 20050706; EP 1171448 A2 20020116; IL 145776 A0 20020725; JP 2003523939 A 20030812; MX PA01010529 A 20020314; NZ 514791 A 20040227
DOCDB simple family (application)
BR 0010681 A 20000414; CA 2369886 A 20000414; CN 00809072 A 20000414; EP 00925966 A 20000414; IL 14577600 A 20000414; JP 2000612315 A 20000414; MX PA01010529 A 20000414; NZ 51479100 A 20000414