EP 1171613 A1 20020116 - DSP-7 DUAL-SPECIFICITY MAP KINASE PHOSPHATASE
Title (en)
DSP-7 DUAL-SPECIFICITY MAP KINASE PHOSPHATASE
Title (de)
DSP-7 DOPPEL-SPEZIFIZITÄT MAP KINASE PHOSPHATASE
Title (fr)
MAP KINASE PHOSPHATASE A DOUBLE SPECIFICITE DSP-7
Publication
Application
Priority
- US 0009257 W 20000407
- US 12820799 P 19990407
- US 13575799 P 19990525
Abstract (en)
[origin: WO0060098A1] Compositions and methods are provided for the treatment of conditions associated with cell proliferation, cell differentiation and/or cell survival. In particular, the dual-specificity phosphatase DSP-7, and polypeptide variants thereof that stimulate dephosphorylation of DSP-7 substrates, are provided. The polypeptides may be used, for example, to identify antibodies and other agents that inhibit DSP-7 activity. The polypeptides and agents may be used to modulate cell proliferation, cell differentiation and cell survival.
IPC 1-7
C12N 15/55; C12N 9/16; C12N 15/11; G01N 33/53; C12Q 1/68; C12Q 1/42; C07K 16/40
IPC 8 full level
G01N 33/50 (2006.01); A61K 45/00 (2006.01); A61P 3/00 (2006.01); A61P 21/00 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); A61P 37/08 (2006.01); A61P 43/00 (2006.01); C07K 16/40 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/16 (2006.01); C12N 15/09 (2006.01); C12N 15/55 (2006.01); C12P 21/08 (2006.01); C12Q 1/02 (2006.01); C12Q 1/42 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01)
CPC (source: EP)
A61P 3/00 (2017.12); A61P 21/00 (2017.12); A61P 35/00 (2017.12); A61P 37/00 (2017.12); A61P 37/08 (2017.12); A61P 43/00 (2017.12); C12N 9/16 (2013.01); C12Y 301/03016 (2013.01); C12Y 301/03048 (2013.01)
Citation (search report)
See references of WO 0060098A1
Citation (examination)
- MARTELL K.J. ET AL: "The "VH1-like" dual-specificity protein tyrosine phosphatases", MOL.CELLS, vol. 8, no. 1, 1998, pages 2 - 11, XP001057593
- CHEN H.-H. ET AL: "Characterization of two distinct dual specificity phosphatases encoded in alternative open reading frames of a single gene located on human chromosome 10q22.2", J.BIOL.CHEM., vol. 279, no. 40, 1 October 2004 (2004-10-01), pages 41404 - 41413
- DATABASE GENBANK [online] 27 August 1998 (1998-08-27), "National Cancer Institute, Cancer Genome Anatomy Project", retrieved from NCBI-ENTREZ Database accession no. AI004443
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0060098 A1 20001012; AU 4210100 A 20001023; CA 2367104 A1 20001012; EP 1171613 A1 20020116; JP 2002540794 A 20021203
DOCDB simple family (application)
US 0009257 W 20000407; AU 4210100 A 20000407; CA 2367104 A 20000407; EP 00921835 A 20000407; JP 2000609588 A 20000407