Global Patent Index - EP 1172355 A1

EP 1172355 A1 20020116 - Salicylic acid derivatives, process for their preparation, agents containing the same as well as their use in combatting harmful fungi

Title (en)

Salicylic acid derivatives, process for their preparation, agents containing the same as well as their use in combatting harmful fungi

Title (de)

Salicylsäure-Derivate, Verfahren zu ihrer Herstellung, sie enthaltende Mittel sowie ihre Verwendung zur Bekämpfung von Schadpilzen

Title (fr)

Dérivés de l'acide salicylique, procédé pour leur préparation, agents les contenant ainsi que leur utilisation pour lutter contre les champignons nuisibles

Publication

EP 1172355 A1 20020116 (DE)

Application

EP 01115054 A 20010621

Priority

DE 10034180 A 20000713

Abstract (en)

Hydrazonomethyl-salicylic acid (I) derivatives are new. The hydrazonomethyl-salicylic acid derivatives are compounds of formula (I). X = halo, NO2, CN, 1-4C alkyl, or 1-4C alkoxy; m = 0-3; A = OH, 1-4C alkoxy, NH2, NHCH3, or N(CH3)2; R<1> = phenyl, naphthyl, 3-10C cycloalkyl, 5- or 6-membered heteroaryl or heterocyclyl containing 1-3 N and/or 1 O or S or 1 or 2 O and/or S (each optionally substituted with 1-3 Ra); Ra = CN, NO2, NH2, H2NCO-, H2NCS-, halo, OH, 1-6C alkyl or 1-6C alkoxy (each optionally substituted with halo), 1-6C alkylcarbonyl, 1-6C alkylsulfonyl, 1-6C alkylsulfoxyl, 3-6C cycloalkyl, 1-6C alkoxycarbonyl, 1-6C alkylthio, NH(1-6C alkyl), N(1-6C alkyl)2, 1-6C alkyl-NH-CO-, (1-6C alkyl)2N-CO-, 1-6C alkyl-NH-CS-, (1-6C alkyl)2N-CS-, 2-6C alkenyl, 2-6C alkenyloxy, phenyl, phenoxy, benzyl, benzyloxy, 5- or 6-membered heterocyclyl, heteroaryl or heteroaryloxy, C(=NOR alpha )-OR beta , or OC(R alpha )2-C(R beta )=NOR beta , and cyclic groups are optionally substituted with 1-3 Rb; Rb = CN, NO2, NH2, H2NCO-, H2NCS-, halo, OH, 1-6C alkyl or 1-6C alkoxy (each optionally substituted with halo), 1-6C alkylcarbonyl, 1-6C alkylsulfonyl, 1-6C alkylsulfoxyl, 3-6C cycloalkyl, 1-6C alkoxycarbonyl, 1-6C alkylthio, NH(1-6C alkyl), N(1-6C alkyl)2, 1-6C alkyl-NH-CO-, (1-6C alkyl)2N-CO-, 1-6C alkyl-NH-CS-, (1-6C alkyl)2N-CS-, 2-6C alkenyl, 2-6C alkenyloxy, 3-6C cycloalkenyl, phenyl, phenoxy, phenylthio, benzyl, benzyloxy, 5- or 6-membered heterocyclyl, heteroaryl or heteroaryloxy, or C(=NOR alpha )-OR beta ; R alpha and R beta = H or 1-6C alkyl; R<2> = H, CN, or 1-6C alkyl, 2-6C alkenyl, 2-6C alkynyl, 1-6C haloalkyl, 1-6C alkoxy or 1-6C alkylthio (each optionally substituted with 1 or more halo and/or 1-3 Rc); Rc = halo, CN, NO2, OH; 1-6C alkyl or 1-6C alkoxy (each optionally substituted with halo); 1-6C alkylcarbonyl, 3-6C cycloalkyl, 1-6C alkoxycarbonyl, 1-6C alkylthio, NH(1-6C alkyl), N(1-6C alkyl)2, 2-6C alkenyl, 3-6C alkenyloxy, 3-6C alkynyloxy, or 1-4C alkylenedioxy (optionally halogenated). An Independent claim is also included for the preparation of compounds (I).

Abstract (de)

Salicylsäure-Derivate der Formel I, <IMAGE> in der der Index und die Substituenten folgende Bedeutung haben: X: Halogen, NO2, Cyano, Alkyl oder Alkoxy; m: 0, 1, 2 oder 3, wobei die Substituenten X verschieden sein können, wenn n größer als 1 ist; A: OH, Alkoxy, NH2, NHCH3 oder N(CH3)2; R<1>: Phenyl, Naphthyl, Cycloalkyl, 5-gliedriges oder 6-gliedriges Hetaryl oder 5-gliedriges oder 6-gliedriges Heterocyclyl, enthaltend ein bis drei N-Atome und/oder ein O- oder S-Atom oder ein oder zwei O- und/oder S-Atome, wobei die Ringsysteme unsubstituiert oder substituiert sind; R<2>: Wasserstoff, Cyano, Alkyl, Alkenyl, Alkinyl, Halogenalkyl, Alkoxy oder Alkylthio, Verfahren zur Herstellung dieser Verbindungen, sie enthaltende Mittel sowie ihre Verwendung zur Bekämpfung von Schadpilzen.

IPC 1-7

C07C 251/86; A01N 33/26

IPC 8 full level

C07C 251/80 (2006.01); A01N 33/26 (2006.01); A01N 37/50 (2006.01); C07C 249/16 (2006.01); C07C 251/86 (2006.01)

CPC (source: EP US)

A01N 37/50 (2013.01 - EP US); C07C 251/86 (2013.01 - EP US)

Citation (search report)

  • [A] US 3829492 A 19740813 - MILLER G, et al
  • [AD] WO 9708135 A1 19970306 - BAYER AG [DE], et al
  • [X] A.I. EL-SEBAI ET AL.: "Synthesis of some new acid hydrazides structurally related to certain tuberculostatic agents.", EGYPT. J. PHARM. SCI.,, vol. 14, no. 1, 1973, pages 67 - 73, XP000926689

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

EP 1172355 A1 20020116; EP 1172355 B1 20030827; AT E248142 T1 20030915; DE 50100541 D1 20031002; JP 2002047262 A 20020212; US 2002032178 A1 20020314; US 6593315 B2 20030715

DOCDB simple family (application)

EP 01115054 A 20010621; AT 01115054 T 20010621; DE 50100541 T 20010621; JP 2001207021 A 20010706; US 89697101 A 20010702