EP 1173212 A1 20020123 - CONTRACEPTIVE COMPOSITIONS CONTANING INDOLONE DERIVATIVES AND PROGESTATIONAL AGENTS
Title (en)
CONTRACEPTIVE COMPOSITIONS CONTANING INDOLONE DERIVATIVES AND PROGESTATIONAL AGENTS
Title (de)
EMPFÄNGNISVERHUTENDE ZUSAMMENSETZUNGEN, WELCHE INDOLONE DERIVATEN UND PROGESTATIVE ENTHALTEN
Title (fr)
COMPOSITIONS CONTRACEPTIVES CONTENANT DES DERIVES D'INDOLINE ET DES AGENTS PROGESTATIFS
Publication
Application
Priority
- US 0011834 W 20000501
- US 18305299 P 19990504
- US 55235800 A 20000419
Abstract (en)
[origin: CA2372595A1] This invention relates to cyclic combination therapies and regimens utilizin g substituted indoline derivative compounds which are antagonists of the progesterone receptor having general structure (1), wherein R1 and R2 may be single substituents or fused to form spirocyclic rings, in combination with progestins, estrogens, or both. These methods of treatment may be used for contraception or for the treatment and/or prevention of secondary amenorrhea , dysfunctional bleeding, uterine leiomyomata, endometriosis; polycystic ovary syndrome, carcinomas and adenocarcinomas of the endometrium, ovary, breast, colon, prostate, or minimization of side effects or cyclic menstrual bleedin g. Additional uses of the invention include stimulation of food intake.
IPC 1-7
IPC 8 full level
C07D 401/04 (2006.01); A61K 31/403 (2006.01); A61K 31/404 (2006.01); A61K 31/4439 (2006.01); A61K 31/535 (2006.01); A61K 31/56 (2006.01); A61K 31/57 (2006.01); A61K 45/06 (2006.01); A61P 15/18 (2006.01); C07D 209/34 (2006.01); C07D 209/96 (2006.01); C07D 405/04 (2006.01); C07D 409/04 (2006.01)
CPC (source: EP)
A61K 31/535 (2013.01); A61K 31/56 (2013.01); A61K 31/57 (2013.01); A61K 45/06 (2013.01)
Citation (search report)
See references of WO 0066167A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
AU 4813900 A 20001117; CA 2372595 A1 20001109; CN 1349416 A 20020515; EP 1173212 A1 20020123; JP 2002543158 A 20021217; MX PA01011296 A 20030714
DOCDB simple family (application)
AU 4813900 A 20000501; CA 2372595 A 20000501; CN 00807134 A 20000501; EP 00930287 A 20000501; JP 2000615051 A 20000501; MX PA01011296 A 20000501