EP 1178815 A1 20020213 - DEATH DOMAIN CONTAINING RECEPTORS
Title (en)
DEATH DOMAIN CONTAINING RECEPTORS
Title (de)
DIE "DEATH DOMAIN" ENTHALTENDE REZEPTOREN
Title (fr)
RECEPTEURS CONTENANT UN DOMAINE DE MORT CELLULAIRE
Publication
Application
Priority
- US 0010741 W 20000421
- US 13048899 P 19990422
- US 13674199 P 19990528
Abstract (en)
[origin: WO0064465A1] The present invention relates to novel Death Domain Containing Receptor (DR3 and DR3-V1) proteins which are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR3 and DR3-V1 proteins. DR3 and DR3-V1 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of DR3 and DR3-V1 activity.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/164 (2006.01); A61K 31/436 (2006.01); A61K 31/52 (2006.01); A61K 31/573 (2006.01); A61K 31/675 (2006.01); A61K 38/00 (2006.01); A61K 38/21 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61P 35/00 (2006.01); A61P 37/02 (2006.01); A61P 37/06 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01); C07K 16/28 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); A61P 37/02 (2017.12); A61P 37/06 (2017.12); C07K 14/4747 (2013.01); C07K 14/705 (2013.01); C07K 16/2878 (2013.01); A61K 48/00 (2013.01); C07K 2317/21 (2013.01); C12N 2799/026 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0064465 A1 20001102; AU 4478200 A 20001110; CA 2371114 A1 20001102; EP 1178815 A1 20020213; EP 1178815 A4 20030205; JP 2003522118 A 20030722
DOCDB simple family (application)
US 0010741 W 20000421; AU 4478200 A 20000421; CA 2371114 A 20000421; EP 00926218 A 20000421; JP 2000613455 A 20000421