Global Patent Index - EP 1178828 A1

EP 1178828 A1 20020213 - DEATH DOMAIN CONTAINING RECEPTOR 4

Title (en)

DEATH DOMAIN CONTAINING RECEPTOR 4

Title (de)

"DEATH-DOMAIN"ENTHALTENDER REZEPTOR

Title (fr)

RECEPTEUR 4 CONTENANT LE DOMAINE DE LA MORT CELLULAIRE PROGRAMMEE

Publication

EP 1178828 A1 20020213 (EN)

Application

EP 00932061 A 20000505

Priority

  • US 0012163 W 20000505
  • US 13292299 P 19990506

Abstract (en)

[origin: WO0067793A1] The present invention relates to novel Death Domain Containing Receptor-4 (DR4) proteins which are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR4 proteins. DR4 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of DR4 activity and methods for using DR4 polynucleotides and polypeptides.

IPC 1-7

A61K 39/395

IPC 8 full level

G01N 33/574 (2006.01); A61K 38/00 (2006.01); A61K 38/21 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 47/48 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 37/02 (2006.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01); C07K 16/28 (2006.01); C07K 19/00 (2006.01); C12N 15/02 (2006.01); C12N 15/09 (2006.01); C12P 21/08 (2006.01)

CPC (source: EP)

A61K 39/39541 (2013.01); A61P 31/12 (2017.12); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 37/02 (2017.12); C07K 14/70578 (2013.01); C07K 14/7151 (2013.01); C07K 16/2878 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01); C12N 2799/026 (2013.01)

C-Set (source: EP)

A61K 39/39541 + A61K 2300/00

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0067793 A1 20001116; WO 0067793 A8 20010525; WO 0067793 A9 20020418; AU 4984300 A 20001121; CA 2373063 A1 20001116; EP 1178828 A1 20020213; EP 1178828 A4 20041013; JP 2002544172 A 20021224

DOCDB simple family (application)

US 0012163 W 20000505; AU 4984300 A 20000505; CA 2373063 A 20000505; EP 00932061 A 20000505; JP 2000616818 A 20000505