EP 1178975 A1 20020213 - GADOLINIUM COMPLEX TETRAMIDES AND USE IN MEDICAL IMAGING
Title (en)
GADOLINIUM COMPLEX TETRAMIDES AND USE IN MEDICAL IMAGING
Title (de)
GADOLINIUM-KOMPLEXTETRAMIDE UND VERWENDUNG IN MEDIZINISCHER ABBILDUNGSVORRICHTUNG
Title (fr)
TETRAMIDES D'UN COMPLEXE DE GADOLINIUM ET APPLICATION EN IMAGERIE MEDICALE
Publication
Application
Priority
- FR 0001382 W 20000519
- FR 9906517 A 19990521
Abstract (en)
[origin: FR2793795A1] Racemic complexes (I) of gadolinium with (1,4,7,10-tetra-azacyclododecane)-1,4,7,10-tetra-(2-glutaric) acid and their base salts, are new. Racemic complexes of formula (I) of gadolinium with (1,4,7,10-tetra-azacyclododecane)-1,4,7,10-tetra-(2-glutaric) acid and their base salts, are new. R = phenyl or 1-8C alkyl (optionally hydroxylated), optionally interrupted by one or more phenyl, alkyl, oxy, amino, or amido optionally substituted by alkyl, with phenyl optionally substituted by OH, Br, Cl, I, 1-8C alkyl, 1-8C alkyleneoxy, NO2, NRxRy, NRxCORy, CONRxRy, COORx and Rx, Ry = H or 1-8C alkyl. An Independent claim is included for preparation of (I).
IPC 1-7
IPC 8 full level
A61K 49/04 (2006.01); A61K 49/06 (2006.01); C07D 257/02 (2006.01)
CPC (source: EP US)
A61K 49/0438 (2013.01 - EP US); A61K 49/06 (2013.01 - EP US); C07D 257/02 (2013.01 - EP US)
Citation (search report)
See references of WO 0071526A1
Designated contracting state (EPC)
DE FR GB IT
DOCDB simple family (publication)
FR 2793795 A1 20001124; FR 2793795 B1 20010803; AU 4765800 A 20001212; EP 1178975 A1 20020213; US 6827927 B1 20041207; WO 0071526 A1 20001130
DOCDB simple family (application)
FR 9906517 A 19990521; AU 4765800 A 20000519; EP 00929648 A 20000519; FR 0001382 W 20000519; US 92658901 A 20011121